2007～2009年我院抗感染药物的应用分析

目的 调查分析我院抗感染药物的使用情况,为临床合理用药和科学管理提供依据.方法 用限定日剂量、用药频度和日治疗费用等客观指标分析药物利用的动态.结果 2007～2009年,头孢菌素类、喹诺酮类和大环内酯类药物名列抗感染药用药金额的前3位.头孢菌素类的头孢克洛、头孢呋辛、头孢氨苄、头孢哌酮/舒巴坦,以及喹诺酮类的左氧氟沙星和大环内酯类的罗红霉素、阿奇霉素和克拉霉素位于消耗金额排序前列.疗效确切、使用方便、不良反应少、价格便宜的一线抗感染药为主要用药,而且以口服制剂为主.常见致病菌的耐药率偏高,尤其对左氧氟沙星的耐药率最高达77.8%.结论 我院抗感染药物的使用存在一定的不合理现象,仍需加强抗感染药物的应用管理.

Analysis on utilization of anti-infection drugs in our hospital between 2007 and 2009

Objective To provide evidences for clinical rational use and scientific management of the anti-infection drugs through investigating the application status of the anti-infection drugs in our hospital.Methods Utilization of anti-infection drugs was analyzed by the index of DDD,DDDs and DDC.Results Cephalosporins,quinolones,macrolides ranked the top three on the consumption sum list of the anti-infection drugs between 2007 and 2009.Cefaclor,cefuroxime,cefalexin,cefoperazone/sulbactam,levofloxacin,roxithromycin,azithromycin and clarithromycin ranked the front rows on the consumption sum list.The most anti-infection drugs used in our hospital were the fist line drugs with certain effect,convenience for application,fewer adverse effect and cheaper price,moreover,mainly for oral administration.Resistance rates of common pathogenic bacteria were relatively high,especially to levofloxacin which had the highest rate of 77.8%.Conclusion The utilization of anti-infection drugs in our hospital was unreasonable in some respects.The application administration of anti-infection drugs still should be strengthened.