主动脉内球囊反搏泵在急性心肌梗死并发心源性休克治疗中的应用

目的 探讨血管再通联合主动脉内球囊反搏泵(IABP)治疗急性心肌梗死合并心源性休克的疗效.方法 研究共分4组:血管再通联合IABP治疗组与非血管再通非IABP治疗组、单血管再通及单IABP治疗组,每组各12例.观察应用IABP及不同方式下治疗心肌梗死合并心源性休克其疗效和30 d病死率的影响并进行比较.结果 血管再通联合IABP与非血管再通非IABP、单血管再通或单IABP治疗相比可明显提高心脏指数[分别为2.42、1.62、1.92、2.01 L/(min·m2)],降低多巴酚丁胺剂量(分别为1.53、17.62、6.01、5.51 g),无器官支持天数(分别为3.9、18.1、10.3、9.0 d)、住院时间(分别为10.1、25.2、15.1、14.6 d)及住ICU时间,明显减低30 d病死率(分别为16.7、66.7、50.0、41.7%),差异均有统计学意义(P<0.05或P<0.01).结论 血管再通联合IABP治疗能有效稳定血流动力学,减少器官支持时间,缩短住院时间,明显降低病死率.

Abstract：

Objective To explore the effect and mortality of intra-aortic balloon pump(IABP)and different ways of treatment of acute myocardial infarction complicated with cardiogenic shock.Methods Research is divided into four groups:recanalization joint IABP treatment compared with non recanalization and non IABP treatment,single recanalization or single IABP treatment,each group of 12 patients,observed and compared the efficacy and 30-day mortality of application within IABP and different ways of treatment of acute myocardial infaretion complicated with cardiogenie shock.Results Reeanalization joint IABP treatment compared with non rlecanalization and non IABP treatment,single recanalization or single IABP treatment,that earl be obviously improve cardiac index[unit:L／(min·m2):2.42,1.62,1.92,2.01],reduce vascular active drug dose(unit:g:1.53,17.62,6.01,5.51),shorten organ support time(unit:d:3.9,18.1,10.3,9.0),shorten hospitalization time(unit:d:10.1,25.2,15.1,14.6)and the ICU hospitalization days(unit:d:6.3,17.7,9.2,9.0),obviously decreased 30-day mortality (unit:％:16.7,66.7,50.0,41.7),The difference existed statistical significance(P<0.05 or P<0.01).Conclusion Recanalization joint IABP treatment Can improve hemodynamic stability and reduce organ support days,hospital stay and mortality.

Clinical application of intra-aortic balloon pump support in patients with acute myocardial infarction complicated with cardiogenic shock

Objective To explore the effect and mortality of intra-aortic balloon pump(IABP)and different ways of treatment of acute myocardial infarction complicated with cardiogenic shock.Methods Research is divided into four groups:recanalization joint IABP treatment compared with non recanalization and non IABP treatment,single recanalization or single IABP treatment,each group of 12 patients,observed and compared the efficacy and 30-day mortality of application within IABP and different ways of treatment of acute myocardial infaretion complicated with cardiogenie shock.Results Reeanalization joint IABP treatment compared with non rlecanalization and non IABP treatment,single recanalization or single IABP treatment,that earl be obviously improve cardiac index[unit:L／(min·m2):2.42,1.62,1.92,2.01],reduce vascular active drug dose(unit:g:1.53,17.62,6.01,5.51),shorten organ support time(unit:d:3.9,18.1,10.3,9.0),shorten hospitalization time(unit:d:10.1,25.2,15.1,14.6)and the ICU hospitalization days(unit:d:6.3,17.7,9.2,9.0),obviously decreased 30-day mortality (unit:％:16.7,66.7,50.0,41.7),The difference existed statistical significance(P<0.05 or P<0.01).Conclusion Recanalization joint IABP treatment Can improve hemodynamic stability and reduce organ support days,hospital stay and mortality.