七氟烷与丙泊酚用于门诊宫腔镜手术麻醉的对比研究

目的 比较七氟烷吸入麻醉与丙泊酚静脉麻醉在门诊宫腔镜手术中的作用.方法 40例宫腔镜手术患者完全随机分为丙泊酚组和七氟烷组,每组各20例.患者入室后常规监测心率、平均动脉压、呼吸频率等,同时应用Narcotrend监测仪监测麻醉深度.2组均在麻醉前静脉注射舒芬太尼.丙泊酚组静脉注射丙泊酚麻醉诱导,术中麻醉维持采用丙泊酚恒速输注,维持麻醉深度在D2-E0.七氟烷组通过面罩吸入七氟烷诱导,术中以七氟烷维持麻醉深度在D2-E0.记录2组患者术前、术中、术毕即刻各项监测数据及不良反应.结果 七氟烷组和丙泊酚组患者麻醉深度至D:时平均动脉压较术前均下降(74±2)mm Hg比(89±3)mm Hg;(68±2)mm Hg比(88±3)mm Hg,P<0.05,1 mm Hg=0.133 kPa],2组麻醉深度至D2时平均动脉压相比,差异有统计学意义(P<0.05).七氟烷组患者的苏醒时间明显短于丙?自酚组的(3.1±0.4)min比(3.6±0.4)min,P<0.05];七氟烷组和丙泊酚组患者各项不良反应(躯体不自主运动、头晕、恶心)的发生率3例(15.0%)比20.O%(4例),10.0%(2例)比15.O%(3例),15.0%(3例)比20.0%(4例)]差异均无统计学意义(P>O.05).结论 在门诊宫腔镜手术中七氟烷吸入麻醉与丙泊酚静脉麻醉相比,对循环的影响小,苏醒平稳、迅速.

Abstract：

Objective To compare the effect of sevoflurane aneshthesia and propofol aneshthesia in outpatient hysteroscopy.Methods Fourty women (ASA class Ⅰ-Ⅱ) undergoing hysteroscopy were randomly divided into propofol group(group P)and sevoflurane group(group S).Routine patient monitoring included heart rate, resplratory rate and non-invasive aterial pressure.All patients were given sufentany before the operation. In group P, patientshad intravenous induction and maintained with propofol to achieve a Narcotrend level of D2-E0.In group S,patients received sevoflurane for induction and maintenance to achieve a Narcotrend level of D2-E0.Hemodynamic date of mean atrial pressure(MAP),heart rate(HR),respiratory rate(RR);recovery time and adverse effect were recorded.Resuits When the depth of anesthesia reached the Narcotrend level of D2,mean arterial pressure Was decreased significantly in group S and group P.Mean arterial pressure in group P was decreased significantly during operation in group S(P<0.05).The recovery time was shorter in group S than that in group P(3.1±0.4)min vs (3.6±0.4)min,P<0.05].The frequency of adverse events was similar between the two groups.Conclusion Sevoffurane anesthesia appears to be superior for outpatient hysteroscopic surgery to propofol anesthesia, with regards to recovery time from anesthesia and the hemodynamic stability.

Comparison of sevoflurane and propofol aneshthesia during hysteroscopy

Objective To compare the effect of sevoflurane aneshthesia and propofol aneshthesia in outpatient hysteroscopy.Methods Fourty women (ASA class Ⅰ-Ⅱ) undergoing hysteroscopy were randomly divided into propofol group(group P)and sevoflurane group(group S).Routine patient monitoring included heart rate, resplratory rate and non-invasive aterial pressure.All patients were given sufentany before the operation. In group P, patientshad intravenous induction and maintained with propofol to achieve a Narcotrend level of D2-E0.In group S,patients received sevoflurane for induction and maintenance to achieve a Narcotrend level of D2-E0.Hemodynamic date of mean atrial pressure(MAP),heart rate(HR),respiratory rate(RR);recovery time and adverse effect were recorded.Resuits When the depth of anesthesia reached the Narcotrend level of D2,mean arterial pressure Was decreased significantly in group S and group P.Mean arterial pressure in group P was decreased significantly during operation in group S(P<0.05).The recovery time was shorter in group S than that in group P(3.1±0.4)min vs (3.6±0.4)min,P<0.05].The frequency of adverse events was similar between the two groups.Conclusion Sevoffurane anesthesia appears to be superior for outpatient hysteroscopic surgery to propofol anesthesia, with regards to recovery time from anesthesia and the hemodynamic stability.