Dynamic changes in cerebral microcirculation and hypoxia in the early stages of diffuse axonal injury |
| |
| Authors: | Jinning Song Xiaobin Liu Jingyu Chen Fenru Zhang Lei Xi |
| |
| Institution: | Jinning Song1,Xiaobin Liu1,Jingyu Chen1,Fenru Zhang2,Lei Xi1 1Department of Neurosurgery,the First Affiliated Hospital,Medical School of Xi'an Jiaotong University,Xi'an 710061,Shaanxi Province,China 2Department of Nuclear Medicine,China |
| |
| Abstract: | This study demonstrated that damage to the cerebral microvasculature,the formation of microthrombi and swelling of vascular endothelial cells occur early and peak 12 hours after injury in a rat model of diffuse axonal injury.Moreover,these pathological changes were most evident in the cerebral cortex.Cerebral microcirculatory dysfunction peaked later and had a shorter duration than axonal injury.In addition,the radioactive imaging agent,99Tcm-4,9-diaza-2,3,10,10-tetramethyldodecan-2,11-dione dioxime,was use... |
| |
| Keywords: | diffuse axonal injury microcirculation hypoxia 99Tcm-4 9-diaza-2 3 10 10-tetramethyldodecan-2 11-dione dioxime radioactive counting brain injury neural regeneration |
| 本文献已被 CNKI 等数据库收录！ |
|
