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Lacunar infarction with leukoaraiosis may aggravate cognitive dysfunction
Authors:Dejin Sun  Xueqin Zhang  Penju Liu  Jiechun Chen  Jinxia Cao  Aixia Zhuang  Qinghong Zeng  Shouqin Feng  Yi Zhang  Ji  ong Jiang
Affiliation:Dejin Sun1,Xueqin Zhang2,Penju Liu3,Jiechun Chen1,Jinxia Cao1,Aixia Zhuang1,Qinghong Zeng1,Shouqin Feng4,Yi Zhang5,Jiandong Jiang11Department of Neurology,Lianyungang Second People's Hospital (Lianyungang Hospital of Bengbu Medical College),Lianyungang 222023,Jiangsu Province,China2Department of Neurology,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China3Department of Neurology,Beijing Anzhen Hospital,China4Neurophysiological Room,Lianyungang...
Abstract:This study semi-quantitatively analyzed the effects of leukoaraiosis.Patients with moderate or severe lacunar infarction were found to exhibit low scores on the Montreal Cognitive Assessment Scale (F=12.02,P=0.000),and prolonged P300 Cz2.0 latency (F=16.04,P=0.000).Correlation analysis revealed that the occurrence of leukoaraiosis was negatively correlated with Montreal Cognitive Assessment scores (r=-0.416,P=0.000),and positively correlated with P300 Cz2.0 latency (r=0.538,P=0.000).These findings indicate ...
Keywords:lacunar infarction  leukoaraiosis  event-related potentials  semi-quantitative analysis  vascular cognitive impairment  
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