Regenerating nerve fiber innervation of extraocular muscles and motor functional changes following oculomotor nerve injuries at different sites |
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| Institution: | Wenchuan Zhang1,Massimiliano Visocchi2,Eduardo Fernandez2,Xuhui Wang1,Xinyuan Li1,Shiting Li1 1Department of Neurosurgery,Affiliated Xinhua Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200092,China 2Istituto di Neurochirurgia-Policlinico Agostino Gemelli,Università Cattolica del Sacro Cuore,Rome 00185,Italy |
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| Abstract: | In the present study, the oculomotor nerves were sectioned at the proximal (subtentorial) and distal (superior orbital fissure) ends and repaired. After 24 weeks, vestibulo-ocular reflex evaluation confirmed that the regenerating nerve fibers following oculomotor nerve injury in the superior orbital fissure had a high level of specificity for innervating extraocular muscles. The level of functional recovery of extraocular muscles in rats in the superior orbital fissure injury group was remarkably superior o... |
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| Keywords: | oculomotor nerve functional reconstruction specific innervations injury sites |
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