2008-2010年苏州市手足口病重症病例流行病学特征分析

目的：分析2008-2010年苏州市手足口病重症病例流行病学特征。方法：收集整理2008-2010年苏州市各医疗机构报告的手足口病疫报卡信息及RT-PCR实验室检测结果,描述手足口病的发病特征、地区分布、人群分布和时间分布。结果：手足口病报告发病32 390例,年发病率89.97/10万,重症380例（1.17%）,死亡6例（0.02%）。3年重症病例发生率呈增加趋势（χ2=373.8,P〈0.001）。全市12个市、区均有手足口病重症病例报告,市、区发病率差异有统计学意义（χ2=138.4,P〈0.001）。4-9月为重症发病高峰。3岁以下重症病例占83.68%,男女性别比为1.90∶1,散居儿童及外来人口发病率高。重症病例病原学以EV71为主。结论：苏州市手足口病的发病率及重症者比例逐年上升,重症病例有明显的年龄、性别、季节和地区差异,对重点地区3岁以下手足口病患者应提高警惕,加强健康教育宣传,加强监测工作。

Analysis of epidemiological characteristic of severe cases of hand-foot-mouth disease in 2008-2010 in Suzhou

Objective： To analyze the epidemiological characteristic of severe cases of HFMD in Suzhou in 2008~2010.Methods： Collected the data of HFMD in Suzhou in 2008-2010 and the results through RT-PCR.Results： 32 390 HFMD cases were reported with the incidence rate of 89.97/100 000 380 cases of severe were reported with the severe incidence rate of 1.17%,6 died and the case fatality rate was 0.02%.The severe incidence rate was increasing and there were significant differences（χ2=373.8,P0.001）.The severe cases of HFMD were reported in every counties and districts.There were significant differences of the HFMD incidences among the counties and districts（χ2=138.4,P0.001）.The peak of severe cases was from April to September.83.68% severe cases were less than 3 years old.The incidence ratio of male to female was 1.90∶1,most cases were diasporas.The main cause of severe cases is EV71.Conclusion： The prevalence of HFMD was serious in Suzhou,incidence were different among ages,sexes,seasons and places,the children aged under3 from key areas should be vigilant and strengthening the surveillance.