Sevoflurane and propofol decrease intraocular pressure equally during non-ophthalmic surgery and recovery |
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Authors: | Sator-Katzenschlager S Deusch E Dolezal S Michalek-Sauberer A Grubmüller R Heinze G Wedrich A |
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Affiliation: | 1 Department of Anaesthesiology and General Intensive Care A, University of Vienna, Austria. 2 Department of Anaesthesiology and General Intensive Care B, University of Vienna, Austria. 3 Department of Medical Computer Science, University of Vienna, Austria. 4 Department of Ophthalmology and Optometrics, University of Vienna, Austria*Corresponding author: Department of Anaesthesiology and General Intensive Care, University of Vienna, Währinger Gürtel 1820, A-1090 Vienna, Austria |
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Abstract: | Background. To provide good control of intraocular pressure(IOP) during anaesthesia and surgery, we conducted a study comparingthe effects on IOP during maintenance and recovery of sevofluranevs propofol anaesthesia in 33 patients (ASA III) undergoingelective non- ophthalmic surgery. Methods. Anaesthesia was induced with propofol 2 mg kg1,fentanyl 2 µg kg1 and vecuronium 0.1 mg kg1.Patients were allocated randomly to receive either propofol48 mg kg1 h1 (group P; n=16)or 1.52.5 vol% sevoflurane (group S; n=17) for maintenanceof anaesthesia. Fentanyl 24 µg kg1was added if necessary. The lungs were ventilated with 50% airin oxygen. Blood pressure, heart rate, oxygen saturation andend-tidal carbon dioxide were measured before and throughoutanaesthesia and in the recovery room. IOP was determined withapplanation tonometry (Perkins) by one ophthalmologist blindedto the anaesthetic technique. Results. There was a significant decrease in IOP after inductionand during maintenance of anaesthesia in both groups. No significantdifferences in IOP between the two groups was found. Conclusion. Sevoflurane maintains the IOP at an equally reducedlevel compared with propofol. Br J Anaesth 2002; 89: 7646 |
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Keywords: | anaesthetics i.v., propofol anaesthetics volatile, sevoflurane analgesics opioid, fentanyl eye, intraocular pressure |
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