慢性肺源性心脏病患者动脉血PaCO2与血清胃泌素水平及幽门螺杆菌的关系

目的了解慢性肺源性心脏病(简称肺心病)患者PaCO2与血清胃泌素水平及幽门螺杆菌的关系,探讨肺心病合并上消化道出血的原因。方法观察组肺心病患者44例均符合1977年全国肺心病会议制定的诊断标准。对照组42例为随机选取的健康成人,两组性别、年龄无差异。PaCO2由本院血气分析室用nova-3型仪器测定,同时测定患者血清胃泌素,由首都医科大学临床检测中心运用放射免疫方法专人测定,用C13呼气实验(C-UBT)检测幽门螺杆菌的感染情况。全部数据以均值±标准差表示(x±s),均数差别显著性以t检验及逐步回归测算确定PaCO2与血清胃泌素及幽门螺杆菌的关系。结果肺心病组与对照组PaCO2、血清胃泌素及幽门螺杆菌两组对照有极显著性差异(P<0.001)。结论肺心病患者血清胃泌素水平较正常人明显升高,且幽门螺杆菌的感染率明显升高,与PaCO2呈正相关,易于并发上消化道出血。

The Relationship among PaCO2 serum Gastrin levels and Helicobacter polori infection in Pulmonary Heart Disease

Objective In order to realize the pathogenesis of upper peptic hem orrhage in pulmonary heart disease ,to discovry the relationship among PaCO2 serum Gastrin levels and Helicobacter polori infection. Methods We investigated the PaCO2 serum Gastrin levels and Helicobacter polori in two groups, 44 pulmona ry heart disease patients(A), 42 healthy volunteer(B). Result The prevalence of Helicobacter polori infection PaCO2 and serum Gastrin levels in pulmonary heart disease patients were signficantly higher than contril. Conclusion The patients of pulmonary heart disease are likely occurred upper peptic hemorrhage ,the path ogenesis is the serum gastrin levels and Helicobacter polori infection are sinnf icantly higher.