| 燃煤型砷中毒病区与非病区人群血清谷胱甘肽-S-转移酶活力的比较 |
| |
| 引用本文： | 苏丽琴,吴珍,刘清,程义斌,康家琦,顾珩,金银龙. 燃煤型砷中毒病区与非病区人群血清谷胱甘肽-S-转移酶活力的比较[J]. 环境与健康杂志, 2009, 26(4): 323-324 |
| |
| 作者姓名： | 苏丽琴 吴珍 刘清 程义斌 康家琦 顾珩 金银龙 |
| |
| 作者单位： | 中国疾病预防控制中心环境与健康相关产品安全所,北京,100021;卫生部疾病预防控制局,北京,100044 |
| |
| 基金项目： | 国家科技攻关计划专题项目(2003BA614A-13-02) |
| |
| 摘 要： | 目的研究燃煤型砷中毒病区与非病区人群血清中谷胱甘肽-S-转移酶(GST)活力间的差异,为燃煤型砷中毒的早期诊断和防治提供科学依据。方法于2005年12月底在贵州某燃煤型砷中毒病区选择79名确诊砷中毒病例作为病例组,61名正常居民作为内对照组;在非病区选择89名正常居民作为外对照组。采用分光光度法测定人群血清GST活力。结果与外对照组[(12.74±4.20)U/ml]相比,病例组和内对照组血清GST活力[分别为(14.63±3.59)U/ml和(14.79±3.17)U/ml]均较高,差异均有统计学意义(P<0.01)。而病例组与内对照组血清GST活力间比较,差异无统计学意义(P>0.05)。结论燃煤型砷中毒病区人群血清中GST活力高于非病区人群,血清中GST活力可作为监测燃煤型砷中毒易感人群的指标之一。
|
| 关 键 词： | 砷中毒 谷胱甘肽-S-转移酶 分光光度法 |
Comparison of Activity of Serum Glutathione-S-transferase between Population in Coal-burning Type Arsenism Endemic Area and in Control Area |
| |
| SU Li-qin,WU Zhen,LIU Qing,et al.. Comparison of Activity of Serum Glutathione-S-transferase between Population in Coal-burning Type Arsenism Endemic Area and in Control Area[J]. Journal of Environment and Health, 2009, 26(4): 323-324 |
| |
| Authors: | SU Li-qin WU Zhen LIU Qing et al. |
| |
| Affiliation: | SU Li-qin,WU Zhen,LIU Qing,et al. Institute of Environmental Health , Related Product Safety,Chinese Center for Disease Control , Prevention,Beijing 100021,China |
| |
| Abstract: | Objective To explore the difference of the activity of glutathione-S-transferase (GST)in the serum between the population in coal-burning type arsenism endemic area and in the control area. Methods Seventy-nine diagnosed arsenism patients were selected as the case group and 61 normal residents were selected as the inner control group in a coal burning-type arsenism endemic area. Eighty-nine normal residents were selected as the outer control group in a control area. The activity of GST in the serum was dete... |
| |
| Keywords: | Arsenism Glutathione-S-transferase Spectrophotometry |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
