罗哌卡因与布比卡因用于腰硬联合麻醉剖宫产的临床效果对比

目的:探讨罗哌卡因与布比卡因用于腰硬联合麻醉剖宫产的临床效果。方法:采用随机双盲对照试验设计,将60例择期行腰硬膜联合麻醉剖宫产产妇按照1:1的比例随机分为罗哌卡因组和布比卡因组。罗哌卡因组:0.75%罗哌卡因2ml,布比卡因组:0.75%布比卡因2ml用脑脊液稀释到3ml注药2ml。结果:两组最高感觉阻滞平面、到达最高阻滞平面时间、感觉恢复时间、麻醉效果无显著性差异(P>0.05),罗哌卡因组感觉起效时间、运动阻滞起效时间明显晚于布比卡因组(P<0.05),运动恢复时间明显快于布比卡因组(P<0.05);罗哌卡因组低血压、心动过缓、恶心呕吐和头晕均少于布比卡因组,其中低血压有显著性差异(P<0.05)。结论:与布比卡因比较,罗哌卡因麻醉效能相似,但运动恢复更快,利于早期下床活动,且不良反应少,更适用于腰硬联合麻醉剖宫产。

Clinical Efficacy Comparion of Ropivacaine and Levobupivacaine for Combined Spinal-Epidural Anesthesia(CSEA) on Caesarean Section

Objective:To investigation the of ropivacaine and levobupivacaine for combined spinal-epidural anesthesia(CSEA) on caesarean section.Methods:Use randomized double-blind controlled trial design,sixty primiparae schedualed for caesarean section were divided into ropivacaine group and bupivacaine group in 1:1 proportion.Ropivacaine group:0.75%ropivacaine 2ml,bupivacaine group:0.75%bupivacaine 2ml was diluted to 3ml with cerebrospinal fluid,injection 2ml.Results:There were no significant difference on the highest sensory block plane,reach the maximum block plane time,sensory recovery time,anesthesia effect in the two groups(P>0.05),sensory onset time,motor block onset time of ropivacaine group was significantly later than that of bupivacaine group(P<0.05), motor recovery was significantly faster than the bupivacaine group(P<0.05);the cases of hypotension,bradycardia,nausea,vomiting and dizziness in ropivacaine group were less than the bupivacaine group,the hypotension cases has significantly differences(P<0.05). Conclusion:Compared with bupivacaine,ropivacaine anesthesia has similar effects,but it has faster motor recovery time,conducive to early ambulation,and has fewer adverse reactions,is more suitable for epidural anesthesia on cesarean section.