不孕不育患者沙眼衣原体感染状况分析

目的:研究广东地区不孕不育患者沙眼衣原体(CT)的感染状况。方法:收集937例不孕不育患者(包括原发不孕不育、继发不孕不育和自然流产病例)的生殖道分泌物标本以及879例正常生育者生殖道分泌物标本,并用胶体金免疫沉析法检测CT抗原。结果:不孕不育组CT感染率为14.94%,显著高于对照组(2.62%);不孕不育女性CT感染率为17.62%,显著高于不育男性的CT感染率(10.93%)。女性原发性不孕、继发性不孕及反复自然流产的CT阳性率分别为16.24%、19.12%、16.67%,三组CT阳性率无统计学意义;男性原发性不育组、继发性不育组的CT性率分别为10.06%、11.65%,差异也无统计学意义。结论:CT感染是引起广东地区男性不育,女性不孕及自然流产的重要病因之一。

The Infection Situation of Chlamydia Trachomatis in Patients with Infertility

Objective:To study the prevalence of Chlamy trachomatis(CT) infection in patients with infertility from Guangdong province.Methods:937 secretion specimens of genital duct were collected from patients with infertility,including primary infertility, secondary infertility and recurrent spontaneous abortion cases;879 secretion specimens of genital duct from fertile persons were collected as contral;and using colloidal gold immuno-precipitation to assay CT antigens in specimens.Results:The Chlamydia trachomatis infection rates of infertility group was 14.94%and significantly higher than normal fertility group(2.62%);and the CT infection rate of infertile women(17.62%) was also significantly higher than infertile men(10.93%).The CT-positive rates of women with primary infertility, secondary infertility and recurrent spontaneous abortion were 16.24%,19.12%and 16.67%,no statistical significance distinguish in the three groups;The CT-positive rates of male patients with primary infertility and secondary infertility were 10.06%,11.65%,there is no statistical significance distinguish between the two groups.Conclusion:CT infection is an important cause of male infertility,female infertility,and spontaneous abortion in Guangdong province.