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帕金森病合并精神障碍的发生率及相关因素分析
引用本文:朱亚兰,郑海燕,杨乔荣. 帕金森病合并精神障碍的发生率及相关因素分析[J]. 中国医药导刊, 2011, 13(10): 1682-1683
作者姓名:朱亚兰  郑海燕  杨乔荣
作者单位:四川广汉市人民医院神经科,广汉,618300
摘    要:目的:了解帕金森病(PD)合并精神障碍的发生率,并分析其相关因素。方法:58例原发性PD人通过精神症状问卷形式及汉密顿抑郁量表、统一PD评分量表Yahr分级、简易智能状态检查量表、匹兹堡睡眠质量指数(PSQI)量表、一般情况调查表进行测查,得出本组PD人合并精神障碍的发生率,并通过显著性检验等统计方法对各种因素的相关性进行分析。结果:PD合并精神障碍的发病率为25.9%(15/58),PDPsy发生的相关因素分别为痴呆、抑郁、睡眠障碍及应用多巴胺受体激动剂4项。结论:PD合并精神障碍具有较高的发病率,是由多种因素共同作用所致。

关 键 词:帕金森病  精神障碍  发生率  相关因素

Incidence and Related Factors of Psychosis in Parkinson Disease
Zhu Ya-lan,Zheng Hai-yan,Yang Qiao-rong. Incidence and Related Factors of Psychosis in Parkinson Disease[J]. Chinese Journal of Medicinal Guide, 2011, 13(10): 1682-1683
Authors:Zhu Ya-lan  Zheng Hai-yan  Yang Qiao-rong
Affiliation:(Department of Neurology,Guanghan People’s Hospital,Sichuan Province,Guanghan 618300,China)
Abstract:Objective:To examine the incidence of psychosis in Parkinson disease(PDPsy) and explore the related factors of PDD. Methods:58 patients with Parkinson disease were investigated and assessed with Neuropsychiatric Inventory(NPI),Hamilton Depression Rating Scale,the Unified Parkinson Disease Scale(UPDRS),Yahr Scale,Mini-Mental State Examination(MMSE),Pittsburgh Sleep Quality Index(PSQI),and self-designed questionnaire.The incidence rate of PDPsy and the related factors of PDPsy were analyzed through SPSS.Result:The incidence rate of PDPsy is 25.9%(15/58).The related factors of PDPsy are dementia,depression,somnipathy,and the use of dopamine agonists.Conclusion:The etiology of PPD might be caused by multiple factors.
Keywords:Parkinson Disease  Psychosis
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