酚妥拉明、硝酸甘油分别联合垂体后叶素治疗支气管扩张咯血的临床疗效对比

目的:分析酚妥拉明和硝酸甘油分别与垂体后叶素联合治疗支气管扩张咯血的疗效。方法:选取2011年6月~2013年6月我院收治的支气管扩张患者80例,随机分为A、B两组各40例,A组患者以酚妥拉明与垂体后叶素联合治疗,B组患者以硝酸甘油与垂体后叶素联合治疗,对两组患者的疗效进行对比分析。结果:A组总有效率为97.5%,B组总有效率为95.0%;A组不良反应率为12.5%,B组不良反应率为10.0%:差异均无统计学意义(P0.05)。A组的止血时间与咯血量明显优于B组,差异显著(P0.05)。结论:酚妥拉明与垂体后叶素联合治疗支气管扩张的疗效与起效时间优于硝酸甘油与垂体后叶素联合治疗,但应注意其临床不良反应等情况。

Compared the Clinical Curative Efficacy of Bronchiectasis Hemoptysis Treated by Phentolamine,Nitroglycerin Combined with Vasopressin Respectively

Objective： To compare the clinical curative efficacy of bronchiectasis hemoptysis treated by phentolamine,nitroglycedn combined vasopressin respectively. Methods：80 Patients with bronchiectasis from June 2011 to June 2013 in our hospital,which were randomly divided into two groups,A group 40 patients were treated with phentolamine and vasopressin combination therapy, B group 40 patients were treated with nitroglycerin and vasopressin combination therapy.The efficacy of two groups were compared.Results：The total effective rate of A group was 97.5%,the total effective rate of B group was 95.0%,there was no statistical significance（P〉0.05）.The adverse reactions of A group was 12.5%,The adverse reactions orb group was 10.0%,there was no statistical significance （P〉0.05）.The bleeding time and hemoptysis of A group were better than the B group,there was statistical significance（P〈0.05）.Conclusion： The efficacy and onset time ofphentolaminc and vasopressin combination therapy are better than the combined treatment of bronchiectasis with nitroglycerin and pituitrin, but more attention should be paid to the clinical adverse reaction etc.