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| 高血压患者颈动脉硬化与动态脉压、动态脉压指数的关系及其危险因素分析 | |
| 引用本文： | 李晖,袁建明,张源明.高血压患者颈动脉硬化与动态脉压、动态脉压指数的关系及其危险因素分析[J].山西医科大学学报,2011,42(4):314-317. |
| 作者姓名： | 李晖 袁建明 张源明 |
| 作者单位： | 1. 新疆医科大学第一附属医院VIP内三科,乌鲁木齐,830054 2. 新疆医科大学第一附属医院科研科 3. 新疆医科大学第一附属医院心脏中心高血压科 |
| 摘 要： | 目的探讨动态脉压(ambulatory pulse pressure,APP)、动态脉压指数(ambulatory pulse pressure index,APPI)对原发性高血压(essential hypertension,EH)患者颈动脉硬化的影响。方法对274例EH患者进行动态血压监测(ABPM)和颈动脉超声检查,分析APP、APPI与颈动脉内膜中层厚度(intimamedia thickness,IMT)关系及颈动脉硬化的相关危险因素。所有病人分为两组:APP(24 hAPP)<60 mmHg组157例和APP≥60 mmHg组117例。结果 274例患者中APP≥60 mmHg组颈动脉IMT明显大于APP<60 mmHg组(P<0.05)。颈动脉IMT斑块阳性和阴性组比较,24 hSBP、24 hMAP、24 hPP差异具有统计学意义。多元Logistic回归分析表明,24 hAPP(OR=1.033,95%CI:1.018-1.048,P=0.000 1)、男性患者(OR=2.07,95%CI:1.183-3.613,P=0.011)及吸烟(OR=1.808,95%CI:1.073-3.046,P=0.026)是颈动脉IMT增加的独立预测指标。结论随着APP的逐渐增大,颈动脉IMT明显增加,24 hAPP、男性及吸烟是颈动脉IMT增加的独立预测指标。 |
| 关 键 词： | 原发性高血压 动态脉压 颈动脉硬化 |
Relationship of carotid atherosclerosis with ambulatory pulse pressure and ambulatory pulse pressure index and its risk factors in patients with essential hypertension |
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| LI Hui,YUAN Jian-ming,ZHANG Yuan-ming.Relationship of carotid atherosclerosis with ambulatory pulse pressure and ambulatory pulse pressure index and its risk factors in patients with essential hypertension[J].Journal of Shanxi Medical University,2011,42(4):314-317. | |
| Authors: | LI Hui YUAN Jian-ming ZHANG Yuan-ming |
| Institution: | LI Hui1,YUAN Jian-ming2,ZHANG Yuan-ming3(1Dept of Cardiovascular Center,First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China,2Scientific Research Management Section,3Dept of High Blood Pressure in Heart Center,First Affiliated Hospital of Xinjiang Medical University) |
| Abstract: | |
| Keywords: | essential hypertension ambulatory pulse pressure carotid atherosclerosis |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |