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红花注射液与2种常用输液配伍的稳定性研究
引用本文:张慧兰,申云飞,霍建富,贺丽娟,陈通威,王宗刚. 红花注射液与2种常用输液配伍的稳定性研究[J]. 山西医科大学学报, 2011, 42(2): 123-125. DOI: 10.3969/J.ISSN.1007-6611.2011.02.007
作者姓名:张慧兰  申云飞  霍建富  贺丽娟  陈通威  王宗刚
作者单位:山西康宝生物制品股份有限公司,长治,046011
摘    要:目的 建立羟基红花黄色素A含量测定的方法,探讨红花注射液在0.9%氯化钠注射液、5%葡萄糖注射液中的稳定性及配伍.方法 在配伍后0,2,4,6,8,24 h取样,采用高效液相法测定红花注射液与0.9%氯化钠注射液、5%葡萄糖注射液配伍液体内羟基红花黄色素A的含量,同时考察配伍液的pH值、微粒.结果 室温条件下(25 ℃...

关 键 词:红花注射液  羟基红花黄色素A  配伍  稳定性

Compatible stability of safflower injection in two different infusions
ZHANG Hui-lan,SHEN Yun-fei,HUO Jian-fu,HE Li-juan,CHEN Tong-wei,WANG Zong-gang. Compatible stability of safflower injection in two different infusions[J]. Journal of Shanxi Medical University, 2011, 42(2): 123-125. DOI: 10.3969/J.ISSN.1007-6611.2011.02.007
Authors:ZHANG Hui-lan  SHEN Yun-fei  HUO Jian-fu  HE Li-juan  CHEN Tong-wei  WANG Zong-gang
Affiliation:ZHANG Hui-lan,SHEN Yun-fei,HUO Jian-fu,HE Li-juan,CHEN Tong-wei,WANG Zong-gang(Shanxi Kangbao Biological Product CO.,Ltd,Changzhi 046011,China)
Abstract:Objective To establish a method for determining the contents of hydroxysafflor yellow A,and explore the stability and compatibility of safflower injection in 0.9% sodium chloride injection or 5% glucose injection.Methods At 0,2,4,6,8,24 h,the contents of hydroxysafflor yellow A in two mixtures of safflower injection and 0.9% sodium chloride injection or 5% glucose injection were determined by HPLC,and the pH value and microparticles were also investigated.Results There was no significant change in the pH va...
Keywords:safflower injection  hydroxysafflor yellow A  compatibility  stability  
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