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下呼吸道感染2310例病原菌学监测及抗生素应用分析
引用本文:程玮,陈明伟.下呼吸道感染2310例病原菌学监测及抗生素应用分析[J].陕西医学杂志,2011,40(1):33-36.
作者姓名:程玮  陈明伟
作者单位:1. 西安市儿童医院呼吸二科,西安交通大学医学院
2. 西安交通大学医学院第一附属医院呼吸内科,西安,710061
摘    要:目的:探讨儿童下呼吸道感染的病原菌学分布及抗生素应用情况。方法:对2310例下呼吸道感染患儿呼吸道深部分泌物标本及血液标本进行细菌培养及药物敏感性试验,并对用药合理性进行分析研究。结果:下呼吸道感染比例较大,株致病菌中,革兰阳性菌占32.86%,革兰阴性菌占64.68%。革兰阳性菌中,耐甲氧西林金黄色葡萄球菌(MRSA)占64.89%,耐甲氧西林表皮葡萄球菌(MRSE)占45.43%,耐青霉肺炎链球菌(PRSP)占60.78%,革兰阴性菌中,大肠杆菌对头孢呋辛、头孢哌酮、哌拉西林、头孢他啶、环丙沙星、氨苄青霉素耐药率均大于50%,铜绿假单胞菌对阿莫西林/克拉维酸耐药率为97.83%,所有革兰阴性菌对氨苄青霉素耐药率均在65%以上。结论:儿童呼吸道感染以下呼吸道感染为主,常用抗革兰阳性菌药物的耐药情况较为普遍,革兰阴性菌耐药率也较高。

关 键 词:呼吸道感染/病因学  呼吸道感染/药物疗法  抗生素类/治疗应用  细胞  培养的  微生物敏感性试验  药物耐受  细菌  儿童

The monitoring lower respiratory tract infection pathogen and analysis the status of antibiotic resistance
Cheng Wei,Chen Mingwei.The monitoring lower respiratory tract infection pathogen and analysis the status of antibiotic resistance[J].Shaanxi Medical Journal,2011,40(1):33-36.
Authors:Cheng Wei  Chen Mingwei
Institution:Cheng Wei Chen Mingwei Department of Respiratory Medicine,the First Affiliated Hospital,Medical School of Xi'an Jiaotong University(Xi'an 710061)
Abstract:Objective: A retrospective study of the experimental method in our hospital in recent years,school children,the distribution of pathogens of respiratory tract infection and antibiotic resistance analysis of the situation, provide the basis for the clinical use of drugs.Methods: Retrospective study we used the method selected 2310 cases in children with lower respiratory tract infection and respiratory secretion samples of deep cases of blood samples for bacterial culture and drug susceptibility testing,rese...
Keywords:Respiratory tract infections/etiology Respiratory tract infections/drug therapy Antibiotics/ therapeutic use Cell  culture Microbial sensitivity test Drug resistance  bacterial Child  
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