| 置管引流并注入白介素-2联合顺铂治疗恶性胸腔积液疗效分析 |
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| 引用本文： | 戴明,竺家琍,朱海骋. 置管引流并注入白介素-2联合顺铂治疗恶性胸腔积液疗效分析[J]. 实用癌症杂志, 2011, 26(2): 181-183 |
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| 作者姓名： | 戴明 竺家琍 朱海骋 |
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| 作者单位： | 上海市第一人民医院宝山分院肿瘤科,200940 |
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| 摘 要： | 目的探讨中央静脉导管胸腔闭式引流后注入白介素-2联合顺铂治疗恶性胸腔积液的疗效。方法 48例恶性胸腔积液患者随机分为2组,均经皮胸腔穿刺,置入中心静脉导管,联合治疗组（A组）25例,胸腔内注200万单位白介素-2和40 mg顺铂;单用顺铂组（B组）23例,胸腔内注入40 mg顺铂。A、B组均接受3次化疗,每次间隔1周。观察2组疗效和不良反应。结果所有患者均获得满意引流效果;A和B组治疗总有效率分别为84.0%和60.9%,差异有统计学意义（P〈0.05）。A组总不良反应发生率高于B组,但差异无统计学意义（P〉0.05）。结论中心静脉置管行胸腔闭式引流术具有创伤小、活动不受限以及引流效果满意等特点。白介素-2不良反应轻,耐受性好,是治疗恶性胸腔积液较好的选择。
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| 关 键 词： | 中心静脉导管 胸腔积液 白介素-2 顺铂 |
Effect of Interleukin-2 and Cisplatin on Patients with Malignant Pleural Effusion through Thoracic Cavity Perfusion Drainage |
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| DAI Ming,ZHU Jia-li,ZHU Hai-cheng. Effect of Interleukin-2 and Cisplatin on Patients with Malignant Pleural Effusion through Thoracic Cavity Perfusion Drainage[J]. The Practical Journal of Cancer, 2011, 26(2): 181-183 |
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| Authors: | DAI Ming ZHU Jia-li ZHU Hai-cheng |
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| Affiliation: | .Department of Oncology,Baoshan Branch of the 1st People′s Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,200940 |
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| Abstract: | Objective To compare the efficacy of central venous catheter for drainage and administration of interleukin-2(IL-2)and/or cisplatin in the treatment of malignant pleural effusions.Methods Forty-eight patients with malignant pleural effusion were randomly divided into two groups.After percutaneous puncture,all the patients were embedded with a central venous catheter.Combinated therapy group(group A)was 25 cases given 200-million unit IL-2 plus 40mg cisplatin;while cisplatin group(group B) was 23 cases with ... |
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| Keywords: | Central venous catheter Pleural effusions Interleukin-2 Cisplatin |
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