| 三维适形低分割高剂量放射治疗非小细胞肺癌的临床探讨 |
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| 引用本文： | 崔立春,耿会生,党升强,王璇,杨正浩,杜建飞,田春琴,许世成. 三维适形低分割高剂量放射治疗非小细胞肺癌的临床探讨[J]. 现代肿瘤医学, 2011, 19(2): 283-285. DOI: 10.3969/j.issn.1672-4992.2011.02.25 |
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| 作者姓名： | 崔立春 耿会生 党升强 王璇 杨正浩 杜建飞 田春琴 许世成 |
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| 作者单位： | 陕西西安长安医院,陕西,西安,710018 |
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| 摘 要： | 目的:观察非小细胞肺癌行三维适形低分割高剂量放射治疗的疗效与并发症,探讨适合的分割模式和照射剂量。方法:回顾性分析682例非小细胞肺癌,采用三维适形放射治疗,90%-95%的剂量曲线覆盖PTV,单次分割剂量5Gy,1次/日或隔日,3-5次/周,DT50-70Gy/10-14次,中位照射剂量60Gy/12次,等效生物剂量88-90Gy。结果:682例患者中,完全缓解(CR)87例(12.8%),部分缓解(PR)561例(82.2%),总有效率(CR+PR)为95%,其中III级以上放射性肺炎发生率5.2%(36/682),未出现明显的放射性食管炎。结论:非小细胞肺癌采用三维适形低分割高剂量放射治疗(5Gy/次,每周3-5次,中位照射剂量60Gy/12次),是相对安全的;而且局部控制率高,有较好的近期疗效,并发症低,值得推广使用。
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| 关 键 词： | 非小细胞肺癌 适形放疗 低分割治疗 |
Clinical research of three dimensional conformal hypofractionated hige dose radiotherapy(3DCRT) for non small cell lung cancer(NSCLC) |
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| CUI Li-chun,GENR Hui-sheng,DANG Sheng-qiang,WANG Xuan,YANG Zheng-hao,DU Jian-fei,TIAN Chun-qin,XU Shi-cheng. Clinical research of three dimensional conformal hypofractionated hige dose radiotherapy(3DCRT) for non small cell lung cancer(NSCLC)[J]. Journal of Modern Oncology, 2011, 19(2): 283-285. DOI: 10.3969/j.issn.1672-4992.2011.02.25 |
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| Authors: | CUI Li-chun GENR Hui-sheng DANG Sheng-qiang WANG Xuan YANG Zheng-hao DU Jian-fei TIAN Chun-qin XU Shi-cheng |
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| Affiliation: | CUI Li-chun,GENR Hui-sheng,DANG Sheng-qiang,WANG Xuan,YANG Zheng-hao,DU Jian-fei,TIAN Chun-qin,XU Shi-cheng Department of Oncology Chang'an Hospital,xi'an 710018 China |
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| Abstract: | Objective:To analyze the curative effects and side effects of three dimensional conformal hypofractionated high dose radiotherapy(3DCRT) for non small cell lung cancer(NSCLC),to explore the fraction and the dose in NSCLC treatment.Methods: To review and analyse the data of 682 NSCLC patients treated by 3DCRT,PTV was covered by the dose of 90%-95%,the fraction dose was 5Gy.They were treated once a day or once two days,3-5 times/week,DT 50-70Gy/10-14 times,the median dose 60Gy/12F.Results: Of 682 NSCLC patien... |
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| Keywords: | NSCLC 3DCRT hypofractionated radiotherapy |
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