类天疱疮的分型及几种新的亚型

类天疱疮是一组常见的自身免疫性大疱性皮肤病.近年来随着免疫印迹技术的发展,发现几种新的类天疱疮,如抗p200类天疱疮、抗p105类天疱疮及抗p450类天疱疮等.介绍类天疱疮的临床分型、盐裂皮肤间接免疫荧光分型和分子免疫学分型,并对新近命名的抗p200类天疱疮、抗p105类天疱疮及抗p450类天疱疮的临床特征及诊断治疗进行介绍.

Classification and several new subtypes of pemphigoid

Pemphigoid is a group of common autoimmune bl istering disease,which can be cl assified into several clinical categories,such as bullous pemphigoid,gestational pemphigoid and mucous membrane pemphigoid.With the development of immunoblotting technology in recent years,some new variations of pemphigoid have been defined,e.g.,anti-p200 pemphigoid,anti-p105 pemphigoid and anti-p450 pemphigoid.This article introduces the clinical variations.split skin indirect immunofluorescence-based variations,molecular immunological variations of pemphigoid,and describes the clinical features,diagnosis and treatment of some newly defined types of pemphigoid.