抗生素骨水泥填充技术联合自体富血小板血浆对慢性创面修复效果及患者生活质量的影响

目的 探究抗生素骨水泥填充技术联合自体富血小板血浆修复慢性创面的效果及患者生活质量的影响。方法 选取2023年4月-2024年4月于我院接受慢性创面修复治疗的70例患者为研究对象，采用随机数字表法分为对照组和观察组，各35例。对照组给予自体富血小板血浆治疗，观察组给予抗生素骨水泥填充技术联合自体富血小板血浆治疗，比较两组临床相关指标、修复效果、生活质量、肉芽成熟率及治疗满意度。结果 观察组创面愈合时间短于对照组，创面缩小率、肉芽组织生长厚度均大于对照组（P＜0.05）；观察组创面修复总有效率为94.29%，高于对照组的80.00%（P＜0.05）；观察组生理功能、心理功能、社会功能、活力评分均高于对照组（P ＜0.05）；观察组肉芽成熟率为77.14%，高于对照组的54.29%（P ＜0.05）；观察组治疗满意度为97.14%，高于对照组的85.71%（P ＜0.05）。结论 采用抗生素骨水泥填充技术联合自体富血小板血浆治疗慢性创面修复效果较佳，可促进肉芽组织生长、成熟，加快创面愈合，提高患者生活质量水平和治疗满意度，值得临床应用。

Effect of Antibiotic Bone Cement Filling Technique Combined with Autologous PlateletrichPlasma on Chronic Wound Repair and Quality of Life

Objective To explore the effect of antibiotic bone cement filling technology combined with autologous plateletrichplasma on repairing chronic wounds and the quality of life. Methods A total of 70 patients who received chronic woundrepair in our hospital from April 2023 to April 2024 were selected as the research objects. They were divided into controlgroup and observation group by random number table method, with 35 patients in each group. The control group was treatedwith autologous platelet-rich plasma, and the observation group was treated with antibiotic bone cement filling techniquecombined with autologous platelet-rich plasma. The clinical related indexes, repair effect, quality of life, granulationmaturation rate and treatment satisfaction were compared between the two groups. Results The wound healing time of theobservation group was shorter than that of the control group, and the wound reduction rate and granulation tissue growththickness were higher than those of the control group (P <0.05). The total effective rate of wound repair in the observationgroup was 94.29%, which was higher than 80.00% in the control group (P <0.05). The scores of physiological function,psychological function, social function and vitality in the observation group were higher than those in the control group(P <0.05). The granulation maturation rate of the observation group was 77.14%, which was higher than 54.29% of the controlgroup (P <0.05). The treatment satisfaction of the observation group was 97.14%, which was higher than 85.71% of thecontrol group (P <0.05). Conclusion Antibiotic bone cement filling combined with autologous platelet -rich plasma is effectivein the treatment of chronic wounds, which can promote the growth and maturation of granulation tissue, accelerate wound healing, and improve the quality of life and treatment satisfac tion of patients. It is worthy of clinical application.