心理恐惧对止血带加压性疼痛刺激的预测

目的：研究止血带加压性疼痛对心率（heart rate,HR）、血压（blood pressure,BP）的影响以及实验前受试者心理状况对疼痛反应的预测性。方法受试者为15名健康年轻成年男性。实验前让受试者填写知情同意书,填写6项心理学量表,以便衡量受试者的心理状况。记录其实验前心率与血压。然后进行3次左上臂（非利手边）止血带加压,连续记录受试者疼痛程度（pain intensity,PI）和不适程度（ pain distress,PD）,加压速度为10 mmHg/ s（1 mmHg =0.133 kPa）。同时记录各次加压前的疼痛阈值（pain threshold,PT）及每次加压刺激后的心率和血压。结果1）受试者实验前的恐惧量表测量的结果在正常范围内,与其对应的各次加压性疼痛的疼痛阈值变化之间呈负相关（r1=-0.58,P=0.02）。2）疼痛刺激时,心率会随之增加（P〈0.03）。3）受试者经每次止血带加压性疼痛刺激,疼痛程度和不适程度都会逐渐升高。结论1）恐惧评分可以预测止血带加压性的疼痛阈值。2）疼痛刺激能增加心率。

Prediction of the psychological fear on pain sensitivity

Objective To investigate the prediction of the subject’s psychological level on behavioral pain threshold to cuff-pressure tonic pain test and its effect to physical signs of heart rate（HR） and blood pressure（BP）. Methods Fifteen healthy young male subjects （age：18-29 years） participated in the study. They were asked to fill in the informed consent and 6 psychological questionnaires, which were used to estimate their psychological level. They all were taken the BP and HR before and after the experiment. Then cuff-pressure pain was induced at their left upper（non-dominated） arms. The pain intensities and the pain distresses were recorded when the stimulus was going at the speed of 10 mmHg/ s. Meanwhile, we recorded the pressure-pain thresholds before the stimulus and the HR as well as BP after each cuff-pressure stimulus. Results ① The results of the psychometrics were all in normal limits and the fear level for each subject was negatively correlated with his own values of the 3 cuff pressure pain-thresholds（r= -0. 58, P=0. 02）. ② The HR increased after the pain-test（P〈0. 03）. ③ When teach stimulus was going on, the pain-intensities and the distresses for each subject were increasing gradually. Conclusion ① The result of the fear psychometry can predict the behavioral pain threshold. ② The pain stimulation can increase the HR.