| 姜黄素对人类红白血病细胞（K562）的抑制及诱导分化作用 |
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| 引用本文： | 孟秀香 宋振岚. 姜黄素对人类红白血病细胞（K562）的抑制及诱导分化作用[J]. 大连医科大学学报, 1999, 21(2): 98-100 |
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| 作者姓名： | 孟秀香 宋振岚 |
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| 作者单位： | 大连医科大学检验系 |
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| 摘 要： | 用人类红白血病细胞（Ｋ５６２）为通过细胞计数、ＭＴＴ法测定，形态学观察、ＮＢＴ还原试验及联七胺反应等方法检测了不同浓度姜黄素对体外人Ｋ５６２细胞的作用。结果表明，姜黄素对Ｋ５６２细胞有明显的抑制作用。随浓度增加，抑制作用逐渐增强，形态学观察可见轻微诱导分化作用。鉴于姜黄素对人类红白血病细胞兼有轻微诱经和增殖抑制人艇，提示姜黄素有可能应用于人类红白血病的治疗。
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| 关 键 词： | 姜黄素 K562细胞 细胞毒 诱导分化 |
Effects of curcumin on the inhibition and differentiation induction of K 562 cells |
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| Meng Xiuxiang,Song Zhenlan,Jia Li,et al. Effects of curcumin on the inhibition and differentiation induction of K 562 cells[J]. Journal of Dalian Medical University, 1999, 21(2): 98-100 |
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| Authors: | Meng Xiuxiang Song Zhenlan Jia Li et al |
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| Affiliation: | Meng Xiuxiang,Song Zhenlan,Jia Li,et al Department of Clinical Laborotory,Dalian Medical University |
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| Abstract: | In vitro effrcts of different concentration of curcumin has been studied on the K 562 cells(human erythrocytic leukemic cells)with methods of cell counting,MTT,morphology and Benzdine reaction.Results showed that curcumin had significant inhibition effect on K 562 with dose dependent character.Slight differentiation induction was observed morphologially.It is therefore indicated that curcumin may be used in the treatment of human erythrocytic leukemia. |
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| Keywords: | curcumin K 562 cells differention induction cytoxy |
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