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原发性肝癌和慢性肝病血清HBsAg特异性免疫复合物的检测比较
引用本文:李思光 彭宣宪. 原发性肝癌和慢性肝病血清HBsAg特异性免疫复合物的检测比较[J]. 现代免疫学, 1997, 17(3): 174-176
作者姓名:李思光 彭宣宪
作者单位:南昌大学生物工程研究所!南昌330047(李思光,黄雪芳),厦门大学肿瘤细胞工程国家专业实验室(彭宣宪),西安医科大学生物学教研室!现在清华大学生物系(林琳)
基金项目:江西省自然科学基金资助项目
摘    要:采用捕捉法ELISA,检测31例HBV感染指标阳性的原发性肝癌患者血清四类HBsAg特异性免疫复合物。结果表明,各类的阳性率均非常显著低于慢性活动性乙肝和乙肝后肝硬化,而与慢性迁延性乙肝无明显差异。提示患者的免疫抑制程度与慢迁肝基本一致。

关 键 词:原发性肝癌  循环免疫复合物  乙型肝炎表面抗原  酶联免疫吸附试验

Specific Immune Complexes Related to HBsAg in Patients with Primary Hepatocellular Cancer
Li Siguang,Peng Xuanxian,Huang Xuefang,Lin Lin. Specific Immune Complexes Related to HBsAg in Patients with Primary Hepatocellular Cancer[J]. Current Immunology, 1997, 17(3): 174-176
Authors:Li Siguang  Peng Xuanxian  Huang Xuefang  Lin Lin
Abstract:Specific immune complexes related to HBsAg of 31 cases of primary hepa-tocellular cancer with positive markers of HBV infection were determined by antibody capture-ELISA methods. It was found that their positive rates were significantly lower than those of chronic active hepatitis B and liver cirrhosis after hepatitis B infection and were similar to those of chronic persistent hepatitis B. These findings suggest that the immune status of patients with primary hepatocellular cancer is similar to that of ones with chronic persistent hepatitis B.
Keywords:primary hcpatocellular cancer  circulating immune complexes  HBsAg  ELISA
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