| 顺铂并卡莫氟治疗晚期胃肠道恶性肿瘤的效果 |
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| 引用本文： | 郝建波,张良,刘志鸿.顺铂并卡莫氟治疗晚期胃肠道恶性肿瘤的效果[J].青岛大学医学院学报,2008,44(5). |
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| 作者姓名： | 郝建波 张良 刘志鸿 |
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| 作者单位： | 1. 青岛大学医学院附属松山医院,山东,青岛,266021
2. 即墨市人民医院 |
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| 摘 要： | 目的 观察顺铂(DDP)并卡莫氟(HCFU)治疗晚期胃肠道恶性肿瘤的效果及毒性反应.方法 将120例晚期胃肠道恶性肿瘤病人随机分为2组,每组60例.治疗组病人应用DDP、HCFU化疗,对照组应用DDP、氟尿嘧啶(FU)、醛氢叶酸(CF)化疗,评价两组疗效和毒性反应.结果治疗组有效率为40.0%,对照组有效率为30.0%,两组比较差异有显著性(χ2=9.23,P<0.05).治疗组毒性反应较轻.结论 DDP并HCFU治疗晚期胃肠道恶性肿瘤疗效肯定,毒性反应轻,病人耐受性好.
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| 关 键 词： | 卡莫氟 顺铂 胃肠肿瘤 药物疗法 联合 |
CISPLATIN AND CARMOFUR IN TREATMENT OF ADVANCED GASTROINTESTINAL MALIGNANCIES |
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| HAO JIAN-BO,ZHANG LIANG,LIU ZHI-HONG.CISPLATIN AND CARMOFUR IN TREATMENT OF ADVANCED GASTROINTESTINAL MALIGNANCIES[J].Acta Academiae Medicinae Qingdao Universitatis,2008,44(5). |
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| Authors: | HAO JIAN-BO ZHANG LIANG LIU ZHI-HONG |
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| Institution: | HAO JIAN-BO,ZHANG LIANG,LIU ZHI-HONG(The Affiliated Songshan Hospital of Qingdao University Medical College,Qingdao 266021,China) |
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| Abstract: | Objective To study the efficacy and toxicity of cisplatin(DDP) and carmofur(HCFU) for advanced gastrointestinal malignancies(AGM). Methods Patients with AGM,120 cases,were divided evenly into treatment group and control group.The treatment group received DDP and HCFU,and the control group was given DDP,fluorouracil(FU),calcium folinate(CF).The efficacy and toxicity were evaluated. Results The efficacy of treatment and control group was 40.0% and 30.0%,respectively,the difference between the two groups being... |
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| Keywords: | Carmofur Cisplatin Gastrointestinal neoplasms Drug therapy combination |
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