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揿针联合电针治疗气滞血瘀型痔病术后疼痛的临床观察
引用本文:金铭锴,沙静涛,刘慧敏,姚佳. 揿针联合电针治疗气滞血瘀型痔病术后疼痛的临床观察[J]. 中药新药与临床药理, 2024, 41(7): 1798-1804
作者姓名:金铭锴  沙静涛  刘慧敏  姚佳
作者单位:1. 西安市中医医院,陕西西安 710000;2. 西安市中医医院肛肠病医院,陕西西安 710021;3. 福建中医药大学,福建福州 350000;4. 西安市中医药研究院,陕西西安 710021
基金项目:陕西省科学技术厅资助项目(编号:2021SF-403);陕西省中医药管理局资助项目(编号:2021-ZZ-LC004);西安市卫生健康委员会资助项目(编号:2020yb27)
摘    要:【目的】 观察揿针联合电针治疗气滞血瘀型痔病术后疼痛的临床疗效。【方法】 将150例气滞血瘀型痔病术后疼痛患者随机分为观察组、对照组和常规组,每组各50例,常规组给予常规消炎与支持治疗,对照组在常规组治疗的基础上,给予揿针治疗,观察组在对照组治疗的基础上,给予电针治疗。共治疗6 d。治疗6 d后,评价3组临床疗效,观察3组患者治疗前后视觉模拟疼痛量表(VAS)评分的变化情况,比较3组患者治疗前后5-羟色胺(5-HT)、降钙素相关基因肽(CGRP)、去甲肾上腺素(NE)、P物质(SP)、β-内啡肽(β-EP)含量的变化情况。【结果】(1)观察组显效率为36.00%(18/50),对照组为14.00%(7/50),常规组为4.00%(2/50)。观察组显效率明显优于对照组与常规组,差异有统计学意义(P<0.05)。观察组总有效率为100.00%(50/50),对照组为100.00%(50/50),常规组为96.00%(48/50)。观察组与对照组、常规组比较,差异无统计学意义(P>0.05)。(2)治疗后6、12、24、48 h,3组患者的VAS疼痛评分均明显改善(P<0.05),且观察组在改善VAS疼痛评分方面明显优于对照组和常规组,差异有统计学意义(P<0.05)。(3)治疗后,3组患者的血清NE、5-HT、CGRP、SP、β-EP水平均明显改善(P<0.05),且观察组在改善血清 NE、5-HT、CGRP、SP、β-EP水平方面明显优于对照组和常规组,差异均有统计学意义(P<0.05)。【结论】 揿针联合电针治疗气滞血瘀型痔病术后疼痛,能明显改善患者的疼痛症状,患者血清 5-HT、CGRP、NE、SP、β-EP水平均有明显改善,疗效显著。

关 键 词:揿针;电针;气滞血瘀型;痔病;术后疼痛;临床观察

Clinical Observation on the Thumb-tack Needling for SubcutaeousEmbedding Combined with Electroacupuncture in the Treatment ofPostoperative Pain of Hemorrhoids of Qi Stagnation andBlood Stasis Type
JIN Ming-Kai,SHA Jing-Tao,LIU Hui-Min,YAO Jia. Clinical Observation on the Thumb-tack Needling for SubcutaeousEmbedding Combined with Electroacupuncture in the Treatment ofPostoperative Pain of Hemorrhoids of Qi Stagnation andBlood Stasis Type[J]. Traditional Chinese Drug Research & Clinical Pharmacology, 2024, 41(7): 1798-1804
Authors:JIN Ming-Kai  SHA Jing-Tao  LIU Hui-Min  YAO Jia
Affiliation:1. Xi’an Hospital of Traditional Chinese Medicine,Xi’an 710000 Shaanxi,China;2. Anorectal Disease Hospital,Xi’an Hospitalof Traditional Chinese Medicine,Xi’an 710021 Shaanxi,China;3. Fujian University of Traditional Chinese Medicine,Fuzhou350000 Fujian,China;4. Xi’an Academy of Traditional Chinese Medicine,Xi’an 710021 Shaanxi,China
Abstract:Objective To observe the clinical efficacy of thumb-tack needling for subcutaeous embeddingcombined with electroacupuncture in the treatment of postoperative pain of hemorrhoids with qi stagnation and bloodstasis type. Methods A total of 150 patients with postoperative pain of hemorrhoids of qi stagnation and blood stasistype were randomly divided into observation group,control group and routine group,with 50 cases in each group.The routine group was given routine anti-inflammatory and supportive treatment. The control group was giventhumb-tack needling for subcutaeous embedding therapy on the basis of routine group treatment. The observationgroup was given electroacupuncture treatment on the basis of control group treatment. A total of six days of treatments were given. After six days of treatment,the clinical efficacy of the three groups was evaluated,and thechanges of Visual Analogue Scale(VAS)of pain scores were observed before and after treatment in the threegroups. The changes of 5-hydroxytryptamine(5-HT),calcitonin-related gene peptide(CGRP),norepinephrine(NE),substance P(SP)and β-endorphin(β-EP) were compared before and after treatment in the three groups.Results(1)The effective rate of the observation group was 36.00%(18/50),the control group was 14.00%(7/50),and the routine group was 4.00%(2/50). The effective rate of the observation group was significantly superior to thatof the control group and the routine group,and the difference was statistically significant(P<0.05).(2)At 6,12,24,48 hours after treatment,the VAS of pain scores of the three groups were significantly improved(P<0.05),and the improvement of VAS pain score in the observation group was significantly superior to that in thecontrol group and the routine group,the difference was statistically significant(P<0.05).(3)After treatment,the levels of serum NE,5-HT,CGRP,SP and β-EP in the three groups were significantly improved(P<0.05),and the levels of serum NE,5-HT,CGRP,SP and β-EP in the observation group were significantly superior tothose in the control group and the routine group, the differences were statistically significant(P<0.05).Conclusion Thumb-tack needling for subcutaeous embedding combined with electroacupuncture in the treatmentof postoperative pain of hemorrhoids of qi stagnation and blood stasis type can significantly improve the painsymptoms of patients. The levels of serum 5-HT,CGRP,NE,SP and β-EP were significantly improved,andthe curative effect was significant.
Keywords:thumb-tack needling for subcutaeous embedding;electroacupuncture;qi stagnation and blood stasistype;haemorrhoidal disease;postoperative pain;clinical observation
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