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改良CHOP方案治疗老年侵袭性非霍奇金淋巴瘤临床观察
引用本文:张明智,姚志华,耿丽,李鑫. 改良CHOP方案治疗老年侵袭性非霍奇金淋巴瘤临床观察[J]. 肿瘤基础与临床, 2006, 19(3): 209-210
作者姓名:张明智  姚志华  耿丽  李鑫
作者单位:郑州大学第一附属医院肿瘤科,河南,郑州,450052;郑州大学第一附属医院肿瘤科,河南,郑州,450052;郑州大学第一附属医院肿瘤科,河南,郑州,450052;郑州大学第一附属医院肿瘤科,河南,郑州,450052
摘    要:目的应用改良CHOP方案治疗老年侵袭性非霍奇金淋巴瘤(NHL),探讨其疗效和毒副作用。方法选择60~78岁侵袭性非霍奇金淋巴瘤患者,应用改良CHOP方案治疗4~6个周期,观察其疗效。结果CR 17例,PR 8例,RR 89.3%。骨髓抑制、胃肠反应均较轻,心脏毒性发生率低。结论改良CHOP方案治疗老年侵袭性NHL疗效高,毒副作用小。

关 键 词:改良CHOP方案  老年患者  淋巴瘤
文章编号:1673-5412(2006)03-0209-02
收稿时间:2006-01-13
修稿时间:2006-01-13

The Clinical Observation of Elderly Patients with Aggressive Non-Hodgkin's Lymphoma Treated with Improved CHOP Regimen
Zhang Mingzhi,Yao Zhihua,Geng Li,Li Xin. The Clinical Observation of Elderly Patients with Aggressive Non-Hodgkin's Lymphoma Treated with Improved CHOP Regimen[J]. Journal of Basic and Clinical Oncology, 2006, 19(3): 209-210
Authors:Zhang Mingzhi  Yao Zhihua  Geng Li  Li Xin
Affiliation:Department of Oncology, the First Affliated Hospital of Zhengzhou University, Zhengzhou 450052, China
Abstract:Objective To apply improved CHOP regimen to elderly patients with aggressive non-Hodgkin's lymphoma and to exploe its therapeutic effect and adverse reaction.Methods 28 patients with aggressive NHL who were 6078 years old were treated with 4-6 cycles of improved CHOP,its therapeutic effect and adverse reaction were observed.Results CR 17 cases,PR 8 cases,RR 89.3%.Bone marrow depression and gastrointestinal reaction were relatively mild,and incidence rate of cordis toxicity was low.Conclusion This improved CHOP regimen applied to elderly patients with aggressive non-Hodgkin's lymphoma has high therapeutic effect and mild adverse reactions.
Keywords:chemotherapy  persons of advanced age  lymphoma  
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