平消胶囊配合化疗治疗恶性肿瘤32例临床观察

目的：探讨平消胶囊配合化疗治疗恶性肿瘤的，临床疗效。方法：62例患者随机分成两组，治疗组32例采用不同的病种选用相应的化疗方案；肺癌采用EP或NC或GC方案，大肠癌采用5Fu／CF或FOLFOX4方案，肝癌采用HPF或HAF方案＋超液化碘油栓塞方案，胃癌采用ELF或ECF方案，乳腺癌采用AC或CAF方案，鼻咽癌采用DF方案。同时应用平消胶囊分三次口服，每次6粒，每日3次，连服一个月为1疗程，治疗结束后2个月评价疗效。对照纽单纯应用上述方案化疗，不用平消胶囊治疗。观察其临床证候、生活质量、免疫功能及毒副反应等变化。结果：治疗组与对照组总有效率分别为46．9％、33．4％（P〈0．05）；生活质量变化：治疗组与对照组改善率分别为84．4％、60．0％（P〈0．05）；临床证候变化：治疗组与对照组总改善率分别为81．2％、56．7％（P〈0．01）；毒副反应：治疗组血白细胞下降检出率25％，对照组检出率66．7％（P〈0．01）；免疫功能均有不同程度提高，提示平消胶囊配合化疗具有良好的免疫调节作用，并有较好的辅助治疗作用。结论：平消胶囊配合化疗能提高恶性肿瘤患者生活质量、免疫学指标，明显减轻毒副反应，改善临床症状，从而使化疗效果提高，延长生存期。

Clinical observation of treating 32 cases of malignant tumor in Pingxiao capsules plus chemotherapy

Objective： To explore the clinical effect of treating malignant tumor in Pingxiao capsules plus chemotherapy. Methods： 62 cases were randomly divided into two groups, in which, 32 cases in treatment group applying different diseases use the appropriate chemotherapy, such as lung cancer using EP or NC or GC program, colorectal cancer using 5Fu/CF or FOLFOX4, liver cancer using HPF or HAF＋lipiodol embolism program, gastric cancer using ELF or ECF program, breast cancer using AC or CAF program, nasopharyngeal carcinoma using DF program, at the same time, Pingxiao capsules six three oral for 3 times a day, and for a month as a course, then evaluated effects after the treatment finished for 2 months. On contrary, control group only applying above program but no use of Pingxiao capsules, then observe it＇s clinical syndromes, quality of life, immune function and toxicity and other changes. Results： The efficacy rate in two groups were 46.9% and 33.4% （P〈0.05）, the change of quality of life： improvement rate in two groups were 84.4% and 60.0% （P〈0.05）, changes in clinical syndromes： improvement rate in two groups were 81.2% and 56.7% （P〈0.01）, toxicity： Detection rate of treatment group decreased white blood cell is 25%, and detection rate of control group is 66.7% （P〈0.01）. In above cases, immune function were improved, which showed that Pingxiao capsules plus chemotherapy had a good immune regulation, and had better effect of adjuvant therapy.