外敷双柏油膏在肝癌TACE术后肝区疼痛的疗效观察

目的：观察外敷双柏油膏在肝癌经肝动脉化疗栓塞术后肝区疼痛的止痛效果。方法：将63例肝癌TACE术后肝区疼痛患者随机分为治疗组（外敷双柏油膏）33例和对照组（口服止痛西药）30例。对比两组患者治疗前后的疼痛强度、持续时间及用药后的不良反应。结果：在止痛效果方面，两组止痛疗效相近，但治疗组完全缓解率和明显缓解率均略高于对照组。在不良反应方面，治疗组仅个别患者有局部皮肤潮红、轻度瘙痒反应，发生率极低；对照组则见有头晕、呕吐、腹胀、便秘等不良反应，发生率相对较高。结论：对于肝癌TACE术后肝区疼痛患者，使用双柏油膏外敷能够简单、有效地控制疼痛，减少不良反应。

Clinical observation on treating liver pain after TACE surgery with Shuangbaiyou ointment

Objective： To observe the analgesic effect of Shuangbaiyou ointment to the liver pain after transcatheter arterial chemoembolization （TACE）. Methods： Randomly divided 63 cases into treatment group （treated with Shuangbaiyou ointment） with 33 cases and control group （treated with Western medicine） with 30 cases. Two groups were compared with pain intensity, duration, and adverse reactions after treatment. Results： The analgesic effect is similar in two groups, but in the treatment group, the complete remission rate （CR） and part remission rate （PR） was higher than the control group. The adverse reactions occur rate in the treatment group was extremely low. Only few patients in the treatment group had local skin flushing and mild itching. The adverse reactions occurs rate in the control group such as dizziness, vomiting, abdominal distension, constipation and other side effects was relatively high. Conclusion： The therapy of Shuangbaiyou ointment paved on abdomen can be easily and effectively control pain, reduced side effects on patients with liver pain after TACE.