| 白细胞介素8在肿瘤进展中的作用 |
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| 引用本文： | 崔丽焕,吴素慧. 白细胞介素8在肿瘤进展中的作用[J]. 国际免疫学杂志, 2006, 29(4): 260-263 |
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| 作者姓名： | 崔丽焕 吴素慧 |
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| 作者单位： | 030001,太原,山西医科大学附属第一医院妇科;山西医科大学附属第一医院妇科 |
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| 摘 要： | 肿瘤的进展是一多因素、多环节、多阶段的过程,其中肿瘤血管生成起关键作用,近来研究表明肿瘤及肿瘤基质细胞分泌的白细胞介素8(IL8)也是一重要的血管生成因子,它可通过肿瘤及肿瘤血管内皮细胞表面的受体,直接或间接促进肿瘤细胞的增生、新生血管的形成,从而促进肿瘤的生长和转移。
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| 关 键 词： | 白细胞介素-8 肿瘤 血管生成 |
| 文章编号： | 1673-4394(2006)04-0260-03 |
| 收稿时间： | 2005-09-17 |
| 修稿时间： | 2005-09-17 |
The Role of IL-8 in Tumor Progrission |
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| CUI Li-huan. The Role of IL-8 in Tumor Progrission[J]. International Journal of Immunology, 2006, 29(4): 260-263 |
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| Authors: | CUI Li-huan |
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| Affiliation: | The First Teaching Hospital, Shanxi Medical University, Taiyuan 030001, China |
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| Abstract: | Tumor progression is a multistep process including angiogenesis,tumor cell proliferation,migration and tumor-endothelial cell interaction,in which angiogenesis is a key event of tumor growth and metastasis.Recent studies had suggested IL-8 is not only an inflammation cytokine,but also an angiogenic and mitogenic chemokine.IL-8,which secreted by tumor and stromal cells,might stimulate tumor cell proliferation,migration,angiogensis and involve in the invision and metastasis of tumor. |
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| Keywords: | Interleukin-8 Tumor Angiogenesis |
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