夏枯草口服液在不同甲状腺功能状态甲状腺肿大患者中的应用

目的 观察夏枯草口服液在不同甲状腺功能状态对甲状腺大小的影响。方法 56例甲状腺功能亢进（简称甲亢组）、24例甲状腺功能减退（简称甲减组）、18例单纯性甲状腺肿（简称甲肿组）患者随机分为经典治疗组（A1、A2、A3组）和联用夏枯草口服液治疗组（B1、B2、B3组），治疗前后行甲状腺彩超检查甲状腺大小，同时测量20名正常人作为正常对照组。结果 各组治疗前甲状腺均明显大于正常对照组（P〈0．01），治疗后经典治疗组和联用夏枯草口服液治疗组甲状腺均有不同程度缩小，但以联用夏枯草口服液治疗组为明显，与正常对照组比较差异无显著性（P〉0．05）。结论 在不同甲状腺功能状态，治疗甲状腺肿大中西医结合治疗优于单纯用西药治疗。

Clinical Effect of Prunellae Oral Liquid on Goiter with Different Thyroid Function

OBJECTIVE: To observe the clinical effects of Prunellae Oral Liquid (POL) on the size of thyroid with different states of thyroid function in patients of goiter. METHODS: Fifty-six patients with hyperthyroidism, 24 with hypothyroidism and 18 with simple goiter were randomized into two groups. Group A treated by classical therapy, Group B by POL based on classical therapy. Size of thyroid of patients before and after treatment was measured by color ultrasonic Doppler and compared with the data obtained from 20 healthy subjects as control. RESULTS: Size of thyroid in all patients before treatment were obviously larger than that of normal control (P<0.01), but it reduced after treatment in both groups, especially in group B, in which it differed insignificantly to that in the normal control (P > 0.05). CONCLUSION: Combined treatment of Chinese medicine (using POL) and Western medicine is superior to Western medicine alone in treating goiter with different states of thyroid function.