| 核苷类似物抗病毒治疗对慢性HBV感染者短期生存质量的影响 |
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| 引用本文： | 张倩华,张晓红,崇雨田,罗瑞红.核苷类似物抗病毒治疗对慢性HBV感染者短期生存质量的影响[J].吉林医学,2010(1):45-46. |
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| 作者姓名： | 张倩华 张晓红 崇雨田 罗瑞红 |
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| 作者单位： | [1]广东省巾山市第二医院,广东中山528400 [2]中山大学附属三院,广东中山528400 |
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| 摘 要： | 目的:观察核苷类似物抗病毒治疗3个月对慢性HBV感染者生存质量的影响。方法:使用慢性肝病问卷(CLDQ)对慢性HBV感染者抗病毒治疗前及抗病毒治疗3个月进行生存质量评定,并分析抗病毒前后HBVDNA、ALT、AST、TBIL、ALB、PTA变化,了解抗病毒治疗对患者生存质量的影响与病毒载量、肝功能的变化之间的关系。结果:抗病毒治疗3个月后,患者的所有领域生存质量评分均高于治疗前(P<0.05),同时HBVDNA、转氨酶、总胆红素较治疗前下降(P<0.05)。结论:抗病毒治疗不但降低病毒载量、改善肝功能,同时可改善患者生存质量,对有抗病毒治疗指征的患者,应进行抗病毒治疗。
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| 关 键 词： | 抗病毒治疗 生存质量 慢性肝病 问卷 |
Early influence of life quality of patients with chronic HBV infection by antivirus treament with nucleoside analoges |
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| ZHANG Qian-hua,ZHANG Xiao-hong,CHONG Yu-tian,et al.Early influence of life quality of patients with chronic HBV infection by antivirus treament with nucleoside analoges[J].Jilin Medical Journal,2010(1):45-46. |
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| Authors: | ZHANG Qian-hua ZHANG Xiao-hong CHONG Yu-tian |
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| Institution: | 1.The Second Hospital of Zhongshan City;Zhongshan 528400;China;2.The Third Hospital of SUMS;Guangzhou 510000;China |
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| Abstract: | Objective To investigate the impact of life qualities of patients with chronic HBV infection after antiviral treatment of 3 months.Method The life qualities were assessed by CLDQ before and after treatment for 3 months,the changes of HBV-DNA,ALT,AST,TBIL,ALB and PTA were also tested.Results After anti-virus treatment for 3 months,the score of life quality was higher than pretreatment,and HBV-DNA,ALT,TBIL decreased than pretreatment.Conclusion Anti-virus treatment not only reduces HBV-DNA and improves liver ... |
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| Keywords: | Antiviral treament Life quality Chronic liver disease Questionnaire |
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