Advances in the Study of the Mechanism by Which Selenium and Selenoproteins Boost Immunity to Prevent Food Allergies |
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Authors: | Kongdi Zhu Shihui Yang Tong Li Xin Huang Yulan Dong Pengjie Wang Jiaqiang Huang |
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Affiliation: | 1.Beijing Advanced Innovation Center for Food Nutrition and Human Health, Department of Nutrition and Health, China Agricultural University, Beijing 100083, China; (K.Z.); (S.Y.); (T.L.); (X.H.); (Y.D.); (P.W.);2.Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, Ministry of Education, China Agricultural University, Beijing 100083, China;3.College of Veterinary Medicine, China Agricultural University, Beijing 100083, China |
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Abstract: | Selenium (Se) is an essential micronutrient that functions in the body mainly in the form of selenoproteins. The selenoprotein contains 25 members in humans that exhibit a number of functions. Selenoproteins have immunomodulatory functions and can enhance the ability of immune system to regulate in a variety of ways, which can have a preventive effect on immune-related diseases. Food allergy is a specific immune response that has been increasing in number in recent years, significantly reducing the quality of life and posing a major threat to human health. In this review, we summarize the current understanding of the role of Se and selenoproteins in regulating the immune system and how dysregulation of these processes may lead to food allergies. Thus, we can explain the mechanism by which Se and selenoproteins boost immunity to prevent food allergies. |
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Keywords: | selenium selenoprotein immune function food allergy |
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