双途径介入治疗胰腺癌并梗阻性黄疸的效果观察

目的分析经皮胆管内支架置入和肿瘤动脉内灌注化疗的双途径治疗胰腺癌并梗阻性黄疸的疗效。方法16例胰腺癌并梗阻性黄疸患者，先采用经皮肝穿刺胆管内支架置入术，术后10d左右再行胰腺肿瘤供血动脉选择性灌注化疗。结果16例患者全部置入胆管支架，胆汁引流术后1周左右黄疸明显减轻，血清胆红素、谷丙转氨酶明显下降，原发灶得到控制，无严重并发症，能延长患者生存期。平均生存17．7个月。结论经皮胆道支架成形和动脉灌注化疗双介入途径可安全有效治疗胰腺癌并梗阻性黄疸，改善生活质量。

Efficacy of percutaneous placement of biliary stent and intra - arterial for treatment of pancreatic carcinoma and obstructive jaundice

Objectlve To evaluate the therapeutic effect of percutaneous biliary stent and intraarteril for treatment in patients with pancreatic carcinoma and obstructive jaundice. Methods Petcutaneous biliary stenting and intraarterial were performed in 16 patients about 10 days later percutaneous transarterial Chemoembohzation for treatment of pancreatic carcinoma with catcinoma of pancreas and obstructive jaundice. Results 16 biliary stent were planted in all the cases, the jaundice was alleviate significantly, the serum total bilirubin and transaminase were obviously decreased one week after procedure. The primary affection were controlled, there were no severe complications related to the interventional procedure, all patients were followed up with an average of 17.7 months. Concluslons The percutaneous biliary stent and intraarterial embohzation are safe and effective palliative therapies for treatment in patients with pancreatic carcinoma and obstructive jaundice. It can improve the quality of patients hfe.