| 食盐及钙对大鼠血压、血浆钙调素和红细胞膜ATP酶活性的影响 |
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| 引用本文： | 文允镒,罗洪,陈孟勤.食盐及钙对大鼠血压、血浆钙调素和红细胞膜ATP酶活性的影响[J].中国医学科学院学报,1988,10(4):271-275. |
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| 作者姓名： | 文允镒 罗洪 陈孟勤 |
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| 作者单位： | 中国医学科学院基础医学研究所 北京
(文允镒，罗洪)，中国医学科学院基础医学研究所 北京(陈孟勤) |
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| 摘 要： | 观察高、低钠和高、低钙摄入对大鼠血压、血浆钙调素(CaM)和红细胞膜ATP酶活性的影响。结果表明,高钠摄入8周可使大鼠血压显著升高,血清钠和24h尿钠明显高于对照组(P<0.01),血浆CaM水平亦明显升高。高钙摄入能降低血压,24h尿钙和血浆CaM水平明显升高(P<0.05),红细胞膜钙泵活性也提高;而低钙摄入则血压升高,24h尿钙降低(P<0.01)。
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| 关 键 词： | 钠 钙 血压 钙调素 红细胞膜ATP酶 |
Effect of Sodium and Calcium Intake on Blood Pressure, Plasma Calmodulin and Erythrocyte ATPase Activities |
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| Wen Yunyi,et al.Effect of Sodium and Calcium Intake on Blood Pressure, Plasma Calmodulin and Erythrocyte ATPase Activities[J].Acta Academiae Medicinae Sinicae,1988,10(4):271-275. |
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| Authors: | Wen Yunyi |
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| Abstract: | Effects of sodium and calcium intake on blood pressure (BP), plasma calmodulin (CaM) and erythrocyte (RBC) ATPase activities were studied in Wistar rats. The results indicated that BP , serum Na+ and 24h urine Na+ excretion were increased significantly in high-Na-loading rats as compared with that of the control group. High Ca-intake was found to decrease BP with increase of 24 h urine calcium excretion, plasma CaM level and the RBC Ca2+-Mg2+ ATPase activity, while low Ca-intake would cause increase in BP and decrease in 24h urine calcium excretion. |
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| Keywords: | salt calcium blood pressure calmodulin erythrocyte (membrane) ATPase |
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