Early ovarian cancer: 3-D power Doppler |
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Authors: | S Kupesic B M Plavsic |
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Institution: | (1) Department of Gynecology and Obstetrics, “Sveti Duh” Hospital, Medical School University of Zagreb, Sveti Duh 64, 10.000 Zagreb, Croatia;(2) Department of Radiology, Medical Sciences Center, Tulane University, 1430 Tulane Avenue, SL54, New Orleans, LA 70112, USA |
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Abstract: | Transvaginal sonography plays an important role in the assessment of the morphology of ovarian lesions. However, the accuracy
of the technique is limited due to the significant number of false-positive results. Color Doppler imaging and pulsed Doppler
spectral analysis enable evaluation of ovarian tumor blood flow, analysis of the distribution of blood vessels, and quantitative
measurement of blood flow velocity waveforms. These parameters increase the sensitivity and specificity of ultrasound evaluation
of ovarian tumors. Unfortunately, there is no consensus as to which Doppler parameters and cutoff values are the most predictive
of malignancy. Three-dimensional (3-D) power Doppler ultrasound provides a new tool to evaluate features of tumor vascularity.
Three-dimensional ultrasound and 3-D power Doppler imaging in patients with “positive” findings on standard ultrasound tests,
which encompass annual gray-scale transvaginal sonography followed by transvaginal color Doppler ultrasound in selected cases,
represent a novel approach for early and accurate detection of ovarian cancer through screening. Combined evaluations of morphology
and neovascularity by 3-D power Doppler ultrasound may improve early detection of ovarian carcinoma. Contrast-enhanced 3-D
power Doppler sonography facilitates visualization of adnexal tumor vessels, which may aid in differentiating benign from
malignant adnexal lesions. |
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Keywords: | Early ovarian carcinoma Neovascularization Three-dimensional power Doppler ultrasound Three-dimensional ultrasound Transvaginal sonography |
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