| 心力衰竭与急性心肌梗死患者神经内分泌水平的动态观察 |
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| 引用本文： | 葛志强,成民.心力衰竭与急性心肌梗死患者神经内分泌水平的动态观察[J].天津医药,1997,25(4):219-221. |
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| 作者姓名： | 葛志强 成民 |
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| 作者单位： | 中国人民解放军第二五四医院，中国人民解放军第二五四医院，中国人民解放军第二五四医院 300142 天津，300142 天津，300142 天津 |
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| 摘 要： | 通过测定血浆ＰＲＡ、ＡⅡ、Ａｌｄ、ＡＮＰ及ＡＶＰ浓度的变化，研究比较ＣＨＦ和ＡＭＩ时神经内分泌水平的动态演变。发现ＣＨＦ患者神经内分泌水平显著高于ＡＭＩ患者，随着临床症状改善ＣＨＦ患者神经内分泌水平逐渐下降。ＡＭＩ患者各项指标变化不一致。ＰＲＡ及ＡⅡ在住院第４天显著高于１天和第８天的水平，ＡＮＰ及ＡＶＰ血浆浓度在发病第１天最高此后逐渐下降。综上认为，神经内分泌兴奋性的升高是ＣＨＦ发生的主要原因，但
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| 关 键 词： | 心力衰竭 急性 心肌梗塞 神经内分泌 |
Neuroendocfine Changes in Congestive Heart Failure and Acute Myocardial Infarction |
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| Ge Zhiqiang,Cheng Min,Liu Rong The Hospital of PLA,Tianjin.Neuroendocfine Changes in Congestive Heart Failure and Acute Myocardial Infarction[J].Tianjin Medical Journal,1997,25(4):219-221. |
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| Authors: | Ge Zhiqiang Cheng Min Liu Rong The Hospital of PLA Tianjin |
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| Institution: | Ge Zhiqiang,Cheng Min,Liu Rong The 254 Hospital of PLA,Tianjin 300142 |
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| Abstract: | Plasma levels of renin (PRA) ,angiotenin II(AII) ,aldosterone(Ald) ,atrial natriuretic peptide (ANP)and arginine vasopressin (AVP) were measured in patients with congestive heart failure (CHF) or acute myocardial infarction (AMI), The results showed that the levels of all the aforementioned hormones were significantly higher in patients with CHF than with AMI. With amelioration of clinical symptoms of heart failure. elevated neuroendocrine levels decreased slowly from admission till day 8. Neuroendocrine changes in AMI were complex. Plasma PRA and AH concentration were significantly higher on day 4 than on admission and on day 8. Plasma levels of ANP and AVP were shown to be maximal on admission, folio wed by a decline. The study suggested that neuroendocrine activity contributed to the pathogenesis of congestive heart failure. In contrast, AMI caused neuroendocrine activation. |
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| Keywords: | congestive heart failure acute myocardial infarction neuroendocrine |
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