A 20-year follow-up study on the effects of long-term exposure to thorium dust |
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Authors: | Chen Xing'an Cheng Yonge Xiao Huijuan Feng Guodong Deng Yunhui Feng Zhiliang Chen Lian Han Xuanmao Yang Yingjie Dong Zhihuan Zhen Rong |
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Affiliation: | 1. Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China 2. Hospital of Baiyun Obo Rare-earth Iron Mine, Baiyun Obo, Baotou 014080, China |
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Abstract: | OBJECTIVE: To investigate the possible effects of long-term exposure to dust containing thorium and thoron progeny on dust-exposed miners. METHODS: A negative, high voltage, exhaled thoron progeny measurement system was used to estimate the miners' thorium lung burden. RESULTS: The highest thorium lung burden of 638 miners was 11.11 Bq. The incidence of stage 0(+) pneumoconiosis was higher among dust-exposed miners. Lung cancer mortality of the dust-exposed miners was significantly higher than that of controls (P < 0.005). CONCLUSION: There is a difference in cancer rates between those who have long-term exposure to dust containing thorium (in which carcinogenic ThO(2) and SiO(2) exist) and thoron progeny and those who have not. |
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Keywords: | thorium thoron progeny lung cancer |
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