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导数光谱法测定微乳中维生素C的含量
引用本文:张正全,陆彬,杨秀岑. 导数光谱法测定微乳中维生素C的含量[J]. 华西药学杂志, 2001, 16(1): 46-47
作者姓名:张正全  陆彬  杨秀岑
作者单位:华西医科大学药学院,;华西医科大学药学院,;华西医科大学药学院,
摘    要:目的:探讨微乳中药物的测定方法。方法分别利用二阶及三阶导数光谱测定了维生素C(VitC)的O/W及W/O型微乳中VitC的含量。结果:平均回收率及精密度分别达到98.1%,RSD%=0.62(n=12);99.0%,RSD=0.52(n=12)。结论:该法简便,适合Vit微乳的含量测定。为保证结果可靠,样品需作前处理。

关 键 词:微乳  维生素C  二阶导数光谱  三阶导数光谱
文章编号:1006-0103(2001)01-0046-02
修稿时间:2000-06-01

DERIVATIVE SPECTROPHOTOMETRIC DETERMINATION OF VITAMIN C IN MICROEMULSIONS
ZHANG Zheng-quan,LU Bin,YANG Xiu-cen. DERIVATIVE SPECTROPHOTOMETRIC DETERMINATION OF VITAMIN C IN MICROEMULSIONS[J]. West China Journal of Pharmaceutical Sciences, 2001, 16(1): 46-47
Authors:ZHANG Zheng-quan  LU Bin  YANG Xiu-cen
Abstract:OBJECTIVE:To investigate the method for determination of vitamin C in microemulsions. METHODS:The content of vitamin C in O/W microemulsions and W/O microemulsions was determined by second order derivative spectrophotometry and third order derivative spectrophotometry, respectively.RESULTS:The recovery and accuracy are 98.1%, RSD%=0.62 (n =3) and 99.0%, RSD%=0.52 (n =3), respectively.CONCLUSION:This method has the advantage of simplicity and is suitable for determination of the content of vitamin C in microemulsions.
Keywords:Microemulsions  Vitamin C  Second order derivative spectrophotometry  Third order derivative spectrophotometry
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