Antimicrobial susceptibility of multidrug-resistant Streptococcus pneumoniae strains with penicillin MICs of 8 to 32 mg/L |
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| Authors: | Violeta Rodrí guez-Cerrato,Matilde GraciaGema del Prado,Lorena HuelvesPlí nio Naves,Vicente RuizCarmen Ponte,Francisco Soriano |
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| Affiliation: | Department of Medical Microbiology and Antimicrobial Chemotherapy, Fundación Jiménez Díaz-Capio, 28040 Madrid, Spain |
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| Abstract: | The in vitro activity of 22 antibiotics (including novobiocin) and β-lactam/gentamicin combinations was assessed against 11 multidrug-resistant pneumococcal strains. Among orally administered drugs, only telithromycin, levofloxacin, and linezolid were active against all isolates, but their use is not indicated in pediatrics. Novobiocin could be a potential therapeutic alternative. |
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| Keywords: | Streptococcus pneumoniae antibiotic resistance |
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