Investigation of the HPLC response of NSAIDs by fractional experimental design and multivariate regression analysis. Response optimization and new retention parameters |
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| Authors: | Piera Iuliani Giuseppe CarlucciAlessandro Marrone |
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| Institution: | Dipartimento di Scienze del Farmaco, Facoltà di Farmacia-Università degli Studi “G. D’Annunzio” Chieti-Pescara, Via dei Vestini, 66100 Chieti, Italy |
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| Abstract: | The optimization of the HPLC procedures and the investigation of the predictive models are generally seen as distinct tasks although they could be both approached by very similar chemometric methods. |
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| Keywords: | Experimental design MLR analysis Response optimization Retention parameters RP-HPLC |
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