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| 重型颅脑损伤患者呼吸机相关性肺炎的病原菌分布及耐药性分析 | |
| 引用本文： | 吴连根,张金秀,余成. 重型颅脑损伤患者呼吸机相关性肺炎的病原菌分布及耐药性分析[J]. 中华医院感染学杂志, 2010, 20(19) |
| 作者姓名： | 吴连根 张金秀 余成 |
| 作者单位： | 1. 衢州市衢江区人民医院检验科,浙江衢州,324000 2. 衢州市衢江区人民医院医院感染管理科,浙江衢州,324000 3. 衢州市衢江区人民医院神经外科,浙江衢州,324000 |
| 摘 要： | 目的 明确重型颅脑损伤患者呼吸机相关性肺炎(VAP)的病原菌分布及耐药性特点,以期指导临床合理用药.方法 对175例重型颅脑损伤患者在机械通气治疗48 h后,采用一次性无菌吸痰管,经气管插管采集下呼吸道分泌物,作细菌培养、鉴定及药敏试验.结果 122例VAP患者下呼吸道分泌物培养出病原菌316株,病原菌分布:革兰阴性杆菌227株,占71.8%,主要为鲍氏不动杆菌、铜绿假单胞菌、肺炎克雷伯菌、大肠埃希菌,革兰阳性球菌50株,占15.8%,主要为金黄色葡萄球菌、表皮葡萄球菌、肠球菌属,真菌39株,占12.4%,主要为白色假丝酵母菌.结论 重型颅脑损伤患者机械通气治疗时易并发医院肺部感染,主要病原菌为革兰阴性杆菌且存在较严重的耐药现象,混合感染现象严重,应进行病原学监测,以提高治疗成功率. |
| 关 键 词： | 重型颅脑损伤 呼吸机相关性肺炎 病原菌 耐药性 |
Severe Traumatic Brain Injury Patients with Ventilator-associated Pneumonia Distribution of Pathogens and Drug Resistance |
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| WU Lian-gen,ZHANG Jin-xiu,YU Cheng. Severe Traumatic Brain Injury Patients with Ventilator-associated Pneumonia Distribution of Pathogens and Drug Resistance[J]. Chinese Journal of Nosocomiology, 2010, 20(19) | |
| Authors: | WU Lian-gen ZHANG Jin-xiu YU Cheng |
| Abstract: | OBJECTIVE To determine the pathogen distribution and drug resistance characteristics among severe traumatic brain injury patients with ventilator-associated pneumonia(VAP),to guide the clinical use of drugs.METHODS The disposable sterile suction tube was used through the tracheal intubation to collec the lower respiratory tract secretions for bacterial culture,identification and susceptibility test among 175 severe traumatic brain injury patients treated with mechanical ventilation after 48 h.RESULTS 122 ca... |
| Keywords: | Severe traumatic brain injury Ventilator-associated pneumonia Pathogen Drug resistance |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |