| 燃煤型氟骨症患者血清钙、磷及碱性磷酸酶的变化 |
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| 引用本文： | 陈应康,;田培燕,;叶劲松,;莫开勇,;杨小军,;余跃生.燃煤型氟骨症患者血清钙、磷及碱性磷酸酶的变化[J].张家口医学院学报,2008(4):27-28. |
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| 作者姓名： | 陈应康 ;田培燕 ;叶劲松 ;莫开勇 ;杨小军 ;余跃生 |
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| 作者单位： | [1]黔南民族医学高等专科学校病理教研室,贵州都匀558000 |
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| 基金项目： | 黔南民族医学高等专科学校科研项目（编号：QNYZ200703） |
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| 摘 要： | 目的：了解燃煤型氟骨症患者血清Ca、P和ALP的变化。方法：分别测定99例燃煤型氟骨症患者和61例非病区健康人群血清Ca、P和ALP水平。结果：氟骨症患者血清Ca（2．12±0．24mmol／L）明显低于健康对照组（2．51±0．14mmol／L），血清P（1．24±0．4lmmol／L）和ALP（90．22±29．21U／L）明显高于对照组（分别为1．09±0．28mmol／L和73．64±23．93U／L），差异均具有统计学意义（P〈0．01）。结论：在排除其他代谢性骨病的条件下，血清Ca、P和ALP可作为氟骨症辅助诊断的生化指标。
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| 关 键 词： | 钙 磷 碱性磷酸酶 氟骨症 |
Determination of Serum Calcium,Phosphorus and Alkaline Phosphatase in the Patients with Coal Burning Skeletal Fluorosis |
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| Institution: | CHEN Ying-kang, TIAN Pei-yan, YE Jing-song, et al (Qiannan Medical College for Nationalities, Duyun, 558003,Guizhou, China) |
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| Abstract: | Objective： To investigate the changes in levels of serum calcium, phosphorus and alkaline phosphatase in the patients with coal burning skeletal fluorosis. Methods： The biochemical indices,such as calcium, phosphorus and alkaline phosphatase in 99 cases with coal burning skeletal fluorosis and 61 cases in normal control group in non-endemic area were determined. Results： The value of serum calcium （2.12 ±0.24mmol/L） in skeletal fluorosis group was lower than that of normal control group（2.51±0.14mmol/L）（P 〈0.01）, and those of serum phosphorus（ 1.24 ± 0.41mmol/L） and alkaline phosphatase （ 90.22 ± 29.21U/L） were higher than that in normal control group（1.09±0.28mmol/L and 73.64±23.93U/L,respectively ） （P〈0.01）. Conclusions： Serum calcium,phosphorus and alkaline phosphatase could play important roles in auxilia- ry diagnosis of skeletal fluorosis,except other metabolic bone diseases. |
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| Keywords: | Calcium Phosphorus Alkaline Phosphatase OSTEOFLUOROSIS |
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