| 高同型半胱氨酸血症、MTHFR基因多态性与脑血管病 |
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| 引用本文： | 高娟,郭力.高同型半胱氨酸血症、MTHFR基因多态性与脑血管病[J].国际脑血管病杂志,2006,14(7):519-522. |
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| 作者姓名： | 高娟 郭力 |
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| 作者单位： | 050000,石家庄,河北医科大学第二医院神经内科 |
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| 摘 要： | 高同型半胱氨酸血症是脑血管病的独立危险因素之一,亚甲基四氢叶酸还原酶C677T基因突变常常引起血浆同型半胱氨酸水平增高,但亚甲基四氢叶酸还原酶基因多态性与脑血管病的关系并不显著。
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| 关 键 词： | 同型半胱氨酸 亚甲基四氢叶酸还原酶 基因多态性 脑血管病 |
| 收稿时间： | 2006-01-11 |
| 修稿时间： | 2006-03-07 |
Hyperhomocysteinemia, Genetic Polymorphism of Methylenetetrahydrofolate Reductase and Cerebrovascular Diseases |
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| Juan Gao,Li Guo.Hyperhomocysteinemia, Genetic Polymorphism of Methylenetetrahydrofolate Reductase and Cerebrovascular Diseases[J].International Journal of Cerebrovascular Diseases,2006,14(7):519-522. |
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| Authors: | Juan Gao Li Guo |
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| Institution: | Department of Neurology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China |
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| Abstract: | Hyperhomocysteinemia is one of the independent risk factors of cerebrovascular diseases. Methylenetetrahydrofolate reductase (MTHFR) C677T gene mutation often results in the increase of plasma homocysteine levels, but the relationship between the genetic polymorphism of MTHFR and cerebrovascular diseases is not significant. |
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| Keywords: | homocysteine methylenetetrahydrofolate reductase gene polymorphism cerebrovascular disease |
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