PTH improves titanium implant fixation more than pamidronate or renutrition in osteopenic rats chronically fed a low protein diet |
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| Authors: | R. Dayer T. C. Brennan R. Rizzoli P. Ammann |
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| Affiliation: | (1) Division of Bone Diseases (WHO Collaborating Center for Osteoporosis Prevention), Department of Rehabilitation and Geriatrics, Geneva University Hospitals and Faculty of Medicine, 1211 Geneva 14, Switzerland |
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| Abstract: | Summary We evaluated the effects of parathyroid hormone (PTH), pamidronate, or renutrition on osseointegration of titanium implants in the proximal tibia of rats subject to prolonged low-protein diets. PTH improved mechanical fixation, microarchitecture, and increased pull-out strength. Pamidronate or renutrition had lesser effects. PTH can thus improve implant osseointegration in protein-malnourished rats. |
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