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FRAXA premutation associated with premature ovarian failure |
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| Authors: | Angela M. Vianna-Morgante Silvia S. Costa Annunziata S. Pares Ieda T. N. Verreschi |
| Abstract: | A family is described in which six females in three generations experienced premature ovarian failure (POF). In three of them a FRAXA premutation was documented and the carrier status of a fourth female could be inferred, because her son had the fragile X syndrome. These findings provide further evidence for a nonrandom association between POF and the FRAXA premutation. © 1996 Wiley-Liss, Inc. |
| Keywords: | premature ovarian failure premature menopause FRAXA premutation FRAXA heterozygotes |