Bioresorbable polymeric stents: current status and future promise |
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Authors: | Eberhart Robert C Su Shih-Horng Nguyen Kytai Truong Zilberman Meital Tang Liping Nelson Kevin D Frenkel Peter |
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Institution: | Department of Surgery, University of Texas Southwestern Medical Center at Dallas, 5323 Harry, Hines Boulevard, Dallas, TX 75390-9130, USA. robert.eberhart@utsouthwestern.edu |
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Abstract: | Metal stents and, more recently, polymer-coated metal stents are used to stabilize dissections, eliminate vessel recoil, and guide remodeling after balloon angioplasty and other treatments for arterial disease. Bioresorbable polymeric stents are being developed to improve the biocompatibility and the drug reservoir capacity of metal stents, and to offer a transient alternative to the permanent metallic stent implant. Following a brief review of metal stent technology, the emerging class of expandable, bioresorbable polymeric stents is described, with emphasis on developments in the authors' laboratory. |
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