Suicidal behaviors and their relationship with psychotic-like symptoms in children and adolescents at clinical high risk for psychosis |
| |
| Institution: | 1. Boston Children''s Hospital, Department of Psychiatry, 300 Longwood Avenue, Boston, MA 02115, USA;2. Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA;3. McLean Hospital, Department of Psychiatry, 115 Mill Street, Belmont, MA 02478, USA;1. Telethon Kids Institute, The University of Western Australia, 100 Roberts Road, Subiaco, 6008, Western Australia, Australia;2. Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, The Netherlands;3. Child and Adolescence Neuropsychiatry Unit, Department of Neuroscience, Children Hospital Bambino Gesù, Piazza Sant''Onofrio 4, 00165 Rome, Italy;4. School of Psychology, University of Birmingham, Edgbaston B15 2TT, United Kingdom;5. Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Level 3, Alan Gilbert Building, 161 Barry St, Carlton, Victoria 3053, Australia;6. Office Médico-Pédagogique Research Unit, Department of Psychiatry, University of Geneva School of Medicine, Geneva, Switzerland;1. Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong;2. State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong;1. Boston Children''s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA;2. Harvard Medical School, Department of Psychiatry, 401 Park Drive, Boston, MA 02215, USA;3. Beth Israel Deaconess Medical Center, Department of Psychiatry, Commonwealth Research Center, 75 Fenwood Road, Boston, MA 02115, USA;4. Massachusetts General Hospital, Department of Psychiatry, 55 Fruit Street, Boston, MA 02114, USA;5. Harvard Medical School, Department of Neurology, 25 Shattuck Street, Boston, MA 02115, USA;6. E.P. Bradley Hospital and Warren Alpert Medical School, Brown University, Neuroplasticity and Autism Spectrum Disorder Program and Department of Psychiatry and Human Behavior, 1011 Veterans Memorial Parkway, East Providence, RI 02915, USA;7. Beth Israel Deaconess Medical Center, Division of Cognitive Neurology and Berenson-Allen Center, 330 Brookline Avenue, Boston, MA 02115, USA |
| |
| Abstract: | BackgroundPrevious research has demonstrated elevated rates of suicide attempts and ideation in individuals with psychosis. This study investigated rates and severity of suicidal behavior in youth with and at clinical high risk for psychosis, and examined the positive, negative, and disorganized symptoms associated with suicidal behaviors among the clinical high risk group.MethodsEighty-six youth ages 7–18 (n = 21 non-clinical controls NCC], n = 40 clinical high risk CHR], n = 25 diagnosed psychotic disorder PD]) were recruited. CHR and PD participants were identified using the Structured Interview for Prodromal Symptoms (SIPS) and Schedule for Affective Disorders and Schizophrenia for School-Age Children—Present and Lifetime Version (KSADS-PL). All participants completed the Suicide Behaviors Questionnaire-Revised (SBQ-R).ResultsFindings indicated significantly higher levels of suicidal behavior among CHR and PD relative to NCC participants (F = 7.64, p = 0.001). 17.5% of CHR participants had previously attempted suicide. Dysphoric Mood and Odd Behavior or Appearance were significantly correlated with suicidal behavior severity among CHR youth.ConclusionSuicidal behavior was observed with greater frequency and severity in the CHR and PD groups than in the NCC group. CHR suicidal behavior severity was correlated most strongly with Dysphoric Mood and Odd Behavior or Appearance, a relationship which warrants further investigation. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
