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Adult separation anxiety disorder in complicated grief: an exploratory study on frequency and correlates
Institution:1. Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy;2. Columbia University School of Social Work, NY, U.S.A.;1. Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA;2. Department of Behavioral Medicine and Psychiatry, West Virginia University, Morgantown, WV;1. Columbia University School of Social Work, Columbia University, New York, NY;2. Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY;3. New York State Psychiatric Institute, New York, NY;4. Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY;5. Division of Biostatistics, Department of Psychiatry, Columbia University, New York, NY;6. Department of Psychiatry, University of California, San Diego, La Jolla, CA;7. Department of Psychiatry, University of Pittsburgh School of Medicine and Department of Community and Behavioral Health Science, University of Pittsburgh Graduate School of Public Health, Western Psychiatry Institute and Clinic, Pittsburgh, PA;8. Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital, Boston, MA;9. Harvard Medical School, Boston, MA;10. Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY
Abstract:IntroductionComplicated grief (CG) has been the subject of increasing attention in the past decades but its relationship with separation anxiety disorder (SEPAD) is still controversial. The aim of the current study was to explore the prevalence and clinical significance of adult SEPAD in a sample of help-seeking individuals with CG.Methods151 adults with CG, enrolled in a randomized controlled trial comparing the effectiveness of (CG) treatment to that of interpersonal therapy, were assessed by means of the Inventory of Complicated Grief (ICG), the Structured Clinical Interview for DSM-IV, the Hamilton Rating Scale for Depression (HAM-D), the Work and Social Adjustment Scale (WSAS), the Adult Separation Anxiety Questionnaire (ASA-27), the Grief Related Avoidance Questionnaire (GRAQ), the Peritraumatic Dissociative Experiences Questionnaire (PDEQ), and the Impact of Events Scale (IES).Results104 (68.9%) individuals with CG were considered to have SEPAD (ASA-27 score ≥22). Individuals with SEPAD were more likely to have reported a CG related to the loss of another close relative or friend (than a parent, spouse/partner or a child) (p = .02), as well as greater scores on the ICG (p = <.001), PDEQ (p = .004), GRAQ (p < .001), intrusion (p < .001) and avoidance (p = <.001) IES subscales, HAM-D (p < .001) and WSAS (p = .006). ASA-27 total scores correlated with ICG (p < .0001), PDEQ (p < .001) GRAQ (p < .0001) scores and both the IES intrusion (p < .0001) and IES avoidance (p < .0001) subscale scores. People with SEPAD had higher rates of lifetime post-traumatic stress disorder (PTSD) (p = .04) and panic disorder (PD) (p = .01).ConclusionsSEPAD is highly prevalent among patients with CG and is associated with greater symptom severity and impairment and greater comorbidity with PTSD and PD. Further studies will help to confirm and generalize our results and to determine whether adult SEPAD responds to CG treatment and/or moderates CG treatment response.
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