老年慢性心力衰竭患者认知功能障碍的分析

目的探讨慢性心力衰竭(CHF)患者的认知功能水平。方法使用蒙特利尔认知评估量表评估53例CHF患者、53例无CHF的心血管疾病患者及21例对照者的认知水平,分析3组患者认知水平的差异。结果 CHF组认知功能障碍发生率(77.4%)高于无CHF的心血管病组(53.7%)及对照组(38.1%),3组间差异有统计学意义(均为P<0.05),而CHF组的各项认知功能水平均低于其他两组(P<0.05),且随着心功能分级的增高、左心室射血分数的降低,认知功能水平下降。结论 CHF可能在原有心血管疾病基础上加重了认知功能的损害,主要表现在视空间与执行功能、注意、语言、记忆等认知功能领域,心功能受损可能是加重认知功能下降的一个重要因素。

Analysis of cognitive dysfunction in elderly patients with chronic heart failure

Objective To investigate cognitive dysfunction in elderly patients with chronic heart failure （CHF）. Methods A total of 127 patients aged ≥60 years were enrolled in this study and were divided into 3 groups： CHF group （n =53, with CHF）, non-CHF group （n =53, with cardiovascular disease but without CHF） and control group （n =21 ） Cognitive level of all patients was evaluated by using Montreal cognitive assessment scale. Results There were 77.4% of the patients in CHF group, 53.7% in non-CHF group and 38. 1% in control group who had cognitive impairment （P 〈 0. 05 ）. Cognitive score was significantly lower in CHF group than in other 2 groups （both P 〈 0. 05 ）. Cognitive dysfunction was deteriorated with the increase of NYHA classification or decrease of left ventricular ejection fraction. Conclusions Chronic heart failure may be one of the important factors aggravating cognitive impairment.